BDBM576081 Compound 34 (1-(4-chlorobenzyl)-6-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one)::US11466034, Example 34

SMILES Cc1ccc(cc1)S(=O)(=O)n1ccc2c(cn(C)c(=O)c12)-c1cnc2[nH]c(=O)n(Cc3ccc(Cl)cc3)c2c1

InChI Key InChIKey=GFQHTUMQHHMMFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576081   

TargetBromodomain-containing protein 4 [44-167](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576081(Compound 34 (1-(4-chlorobenzyl)-6-(6-methyl-7-oxo-...)
Affinity DataIC50: 107nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [349-460](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576081(Compound 34 (1-(4-chlorobenzyl)-6-(6-methyl-7-oxo-...)
Affinity DataIC50: 31nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent