BDBM576045 6-methyl-4-(2-methyl-1-(4- methylthio)benzyl)-1H-imidazo [4,5-b]pyridin-6-yl)-1H- pyrrolo[2,3-c]pyridin-7(6H)-one::US11466034, Example 3

SMILES CSc1ccc(Cn2c(C)nc3ncc(cc23)-c2cn(C)c(=O)c3[nH]ccc23)cc1

InChI Key InChIKey=GQDUGMPGNVUSLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576045   

TargetBromodomain-containing protein 4 [44-167](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576045(6-methyl-4-(2-methyl-1-(4- methylthio)benzyl)-1H-i...)
Affinity DataIC50: 12.7nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [349-460](Human)
Betta Pharmaceuticals

US Patent
LigandPNGBDBM576045(6-methyl-4-(2-methyl-1-(4- methylthio)benzyl)-1H-i...)
Affinity DataIC50: 3.20nMAssay Description:The assays of BRD4 (D1) and BRD4 (D2) were conducted in a 384-well polystyrene plate. The test compounds were first serially diluted in DMSO and the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
Go to US Patent