BDBM50556692 CHEMBL4789452::US12011433, MPA 290

SMILES COc1ccc(cc1)-c1noc(CC(=O)NCCCCN)c1-c1ccc(OC)cc1

InChI Key InChIKey=XONRBNVUBLFDEI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50556692   

TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50556692(CHEMBL4789452 | US12011433, MPA 290)
Affinity DataIC50: 950nMAssay Description:Inhibition of ovine COX-1 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari "Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50556692(CHEMBL4789452 | US12011433, MPA 290)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human COX-2 assessed as peroxidase activity using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome c oxidase subunit 1(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50556692(CHEMBL4789452 | US12011433, MPA 290)
Affinity DataIC50: 950nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCytochrome c oxidase subunit 2(Sheep)
Itel Telecomunicazioni

US Patent
LigandPNGBDBM50556692(CHEMBL4789452 | US12011433, MPA 290)
Affinity DataIC50: 3.50E+3nMAssay Description:The target compounds were evaluated for their ability to inhibit ovine COX-1 and COX-2 enzyme catalytic activity (percent inhibition at 50 mm, unless...More data for this Ligand-Target Pair
In DepthDetails
US Patent