BDBM50551121 CHEMBL1701619

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CNCc2ccc(OCC(=O)Nc3ccccn3)cc2)[C@@H](O)[C@H]1O

InChI Key InChIKey=GIRGWHQMUQZUOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50551121   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Human)
University of Michigan Medical School

Curated by ChEMBL
LigandPNGBDBM50551121(CHEMBL1701619)
Affinity DataIC50: 5.49E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed