Assay Method Information | |
| ChEMBL_2030341 (CHEMBL4684499) |
Description: | Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrate incubated for 1 hr in presence of [3H]-SAM by liquid scintillation counting method |
Affinity data for this assay | |
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