BDBM50293759 2-(4-methoxyphenylamino)-1-(2-(trifluoromethyl)benzyl)-1H-benzo[d]imidazole-5-carboxylic acid::CHEMBL563846::KSP Inhibitor, 4f

SMILES COc1ccc(Nc2nc3cc(ccc3n2Cc2ccccc2C(F)(F)F)C(O)=O)cc1

InChI Key InChIKey=SHPMBGWORDLKHI-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293759   

TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

LigandPNGBDBM50293759(CHEMBL563846 | KSP Inhibitor, 4f | 2-(4-methoxyphe...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

LigandPNGBDBM50293759(CHEMBL563846 | KSP Inhibitor, 4f | 2-(4-methoxyphe...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human kinesin spindle protein by endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin-like protein KIF3B(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293759(CHEMBL563846 | KSP Inhibitor, 4f | 2-(4-methoxyphe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Kif3BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetKinesin heavy chain isoform 5A(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50293759(CHEMBL563846 | KSP Inhibitor, 4f | 2-(4-methoxyphe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of nKHCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed