BDBM50271661 CHEMBL4128989

SMILES OC(CNCc1c(OCc2ccccc2)ccc2ccccc12)c1ccccc1

InChI Key InChIKey=SSIYPAHHMJMQFK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271661   

LigandPNGBDBM50271661(CHEMBL4128989)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (2 to end residues) /human N-terminal His-tagged MEP50 (2 to end residues) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50271661(CHEMBL4128989)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human N-terminal FLAG-tagged PRMT5 (2 to end)/human N-terminal His-tagged MEP50 (2 to end) expressed in HEK293 cells using biotinylated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 5(Human)
University of Jinan

Curated by ChEMBL
LigandPNGBDBM50271661(CHEMBL4128989)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PRMT5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed