BDBM50162007 (R)-1-(2,6-difluorobenzyl)-3-(2-amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-6-methylpyrimidine-2,4(1H,3H)-dione::3-((R)-2-Amino-2-phenyl-ethyl)-1-(2,6-difluoro-benzyl)-5-(2-fluoro-3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione::3-[(2R)-amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)-6-methylpyrimidin-2,4-dione::CHEMBL179691
SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(C[C@H](N)c2ccccc2)c1=O
InChI Key InChIKey=CJUWBZDJMYYRDG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 88 hits for monomerid = 50162007
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168IMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293NMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203EMore data for this Ligand-Target Pair
Affinity DataIC50: 42.7nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q208DMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203KMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295KMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295QMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302QMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189EMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112FMore data for this Ligand-Target Pair
Affinity DataIC50: 15.2nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F313LMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S186DMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S124AMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L117AMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T51AMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F309QMore data for this Ligand-Target Pair
Affinity DataIC50: 9.20nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q208EMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27AMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111AMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR W291FMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR T190KMore data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Antagonist activity against human GnRH receptor expressed in HEK293 cells co-transfected with pGL4-NFAT promoter AP1-luc assessed as inhibition of 20...More data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cell membranes incubated for 1 hr by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.590nMAssay Description:Displacement of [125I]D-Trp6-LHRH from human GnRH receptor expressed in CHO-K1 cells after 1 hr by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at human GnRH receptor expressed in RBL1 cells assessed as inhibition of GnRH-stimulated inositol phosphate productionMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L300VMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293KMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189AMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR W280FMore data for this Ligand-Target Pair
Affinity DataIC50: 13.9nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y283FMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182AMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F272LMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293AMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K191EMore data for this Ligand-Target Pair
Affinity DataIC50: 980nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K121AMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112KMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290FMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189KMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR A50TMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302AMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H182EMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E111KMore data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y284LMore data for this Ligand-Target Pair
Affinity DataIC50: 262nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290QMore data for this Ligand-Target Pair
Affinity DataIC50: 182nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290LMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from human wild type GnRHRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306EMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24TMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Displacement of [125I]-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24IMore data for this Ligand-Target Pair