BDBM243059 PTP inhibitor, 4k

SMILES Oc1cc(O)c2C(=O)CC(Oc2c1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=JPSPQWKZLGZAHP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 243059   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243059(PTP inhibitor, 4k)
Affinity DataIC50: 2.37E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243059(PTP inhibitor, 4k)
Affinity DataIC50: 8.82E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Yanbian University College of Pharmacy

LigandPNGBDBM243059(PTP inhibitor, 4k)
Affinity DataIC50: 8.54E+3nMpH: 6.5 T: 2°CAssay Description:Briefly, the enzymatic activity of the PTP1B catalytic domain was determinedat 30°C by monitoring the hydrolysis of pNPP. Dephosphorylation of pNPP g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed