BDBM23025 4-methoxyphenyl N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]carbamate::N-arachidonoylserotonin carbamate analogue, 3p

SMILES COc1ccc(OC(=O)NCCc2c[nH]c3ccc(O)cc23)cc1

InChI Key InChIKey=JDUHALWQGIVKRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23025   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

LigandPNGBDBM23025(4-methoxyphenyl N-[2-(5-hydroxy-1H-indol-3-yl)ethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The effect of the test compounds on the enzymatic hydrolysis of [14C]anandamide was evaluated by using membranes prepared from rat brain. [14C]Ethano...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
LigandPNGBDBM23025(4-methoxyphenyl N-[2-(5-hydroxy-1H-indol-3-yl)ethy...)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:The antagonistic effects of test compounds were evaluated using HEK293 cells stably overexpressing human TRPV1. Experiments were carried out by measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed