BDBM209922 6'-Guanidinonaltrindole (6'-GNTI)

SMILES NC(N)=Nc1ccc2c3C[C@@]4(O)[C@@H]5Cc6ccc(O)c7O[C@@H](c3[nH]c2c1)[C@]4(CCN5CC1CC1)c67

InChI Key InChIKey=XDKOGAAFSBGLBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 209922   

TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

LigandPNGBDBM209922(6'-Guanidinonaltrindole (6'-GNTI))
Affinity DataIC50: 0.440nMAssay Description:For antagonist experiments, protein was preincubated with test compounds for 15 min prior to the addition of 100 nM U69,593 and [35S]GTPγS. Reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
The Scripps Research Institute

LigandPNGBDBM209922(6'-Guanidinonaltrindole (6'-GNTI))
Affinity DataIC50: 10.1nMAssay Description:β-Arrestin2 translocation was also studied using the PathHunter β-arrestin assay in CHO-K1 cells expressing the KOR (DiscoveRx, Fremont, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details Article
PubMed