BDBM191645 US9186360, 18

SMILES Cn1c2cccc(CC(=O)Nc3nc(cs3)-c3ccc(c(F)c3)C(F)(F)F)c2c(=O)n(C)c1=O

InChI Key InChIKey=FMIIIXHTXHNZIP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 191645   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191645(US9186360, 18)
Affinity DataIC50: 13.4nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
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TargetTransient receptor potential cation channel subfamily V member 1(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191645(US9186360, 18)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
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TargetTransient receptor potential cation channel subfamily V member 3(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191645(US9186360, 18)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
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TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191645(US9186360, 18)
Affinity DataIC50: 1.32E+3nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
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TargetTransient receptor potential cation channel subfamily M member 8(Human)
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191645(US9186360, 18)
Affinity DataIC50: 1.00E+4nMT: 2°CAssay Description:Radiometric calcium assay was performed as described above with some minor modifications. Assay was carried out in total volume of 200 μl at 30&de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent