BDBM18853 N-(4-hexylphenyl)prop-2-ynamide::Propiolic acid derivative, 8a

SMILES CCCCCCc1ccc(NC(=O)C#C)cc1

InChI Key InChIKey=SYSHNOJOKWQTRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18853   

TargetThyroid hormone receptor alpha [148-410](Human)
St. Jude Research Hospital

LigandPNGBDBM18853(N-(4-hexylphenyl)prop-2-ynamide | Propiolic acid d...)
Affinity DataIC50: 6.89E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta [209-461](Human)
St. Jude Research Hospital

LigandPNGBDBM18853(N-(4-hexylphenyl)prop-2-ynamide | Propiolic acid d...)
Affinity DataIC50: 3.51E+4nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed