BDBM18817 1-(4-hexylphenyl)-3-(pyrrolidin-1-yl)propan-1-one::beta-Aminophenylketone, 3d

SMILES CCCCCCc1ccc(cc1)C(=O)CCN1CCCC1

InChI Key InChIKey=JLKDVLVMCWHHMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 18817   

TargetThyroid hormone receptor alpha [148-410](Human)
St. Jude Research Hospital

LigandPNGBDBM18817(1-(4-hexylphenyl)-3-(pyrrolidin-1-yl)propan-1-one ...)
Affinity DataIC50: 4.30E+3nMpH: 7.2 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta [209-461](Human)
St. Jude Research Hospital

LigandPNGBDBM18817(1-(4-hexylphenyl)-3-(pyrrolidin-1-yl)propan-1-one ...)
Affinity DataIC50: 2.70E+3nMAssay Description:IC50 is the concentration of each compound required to inhibit 50% of the binding between the TR LBD and the SRC2-2 peptide using fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed