16 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Naturally occurring polyphenol, morin hydrate, inhibits enzymatic activity of N-methylpurine DNA glycosylase, a DNA repair enzyme with various roles in human disease.
Georgetown University
Influence of the length and positioning of the antiestrogenic side chain of endoxifen and 4-hydroxytamoxifen on gene activation and growth of estrogen receptor positive cancer cells.
Georgetown University
Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands.
Georgetown University
Binding modes of 6,7 di-substituted 4-anilinoquinoline-3-carbonitriles to EGFR.
Georgetown University
Design, synthesis and biological evaluation of Nucleosidic CD99 inhibitors that selectively reduce Ewing sarcoma viability.
Georgetown University
Pharmaceutical compositions for preventing or treating degenerative brain disease and method of screening the same
Korea Institute of Science and Technology
Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR.
University of Texas Southwestern Medical Center
Benzobis(imidazolium)-cucurbit[8]uril complexes for binding and sensing aromatic compounds in aqueous solution.
University of Cambridge
Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity.
Johnson & Johnson Pharmaceutical
Second generation of BACE-1 inhibitors part 2: Optimisation of the non-prime side substituent.
Gsk
Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds.
Scripps Florida
Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents.
Bristol-Myers Squibb