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16 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Naturally occurring polyphenol, morin hydrate, inhibits enzymatic activity of N-methylpurine DNA glycosylase, a DNA repair enzyme with various roles in human disease.EBI
Georgetown University
Influence of the length and positioning of the antiestrogenic side chain of endoxifen and 4-hydroxytamoxifen on gene activation and growth of estrogen receptor positive cancer cells.EBI
Georgetown University
Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands.EBI
Georgetown University
Selectivity and potency of cyclin-dependent kinase inhibitors.EBI
Georgetown University
Binding modes of 6,7 di-substituted 4-anilinoquinoline-3-carbonitriles to EGFR.EBI
Georgetown University
Design, synthesis and biological evaluation of Nucleosidic CD99 inhibitors that selectively reduce Ewing sarcoma viability.EBI
Georgetown University
Therapeutic compounds and uses thereofBDB
Genentech
Pharmaceutical compositions for preventing or treating degenerative brain disease and method of screening the sameBDB
Korea Institute of Science and Technology
Viral polymerase inhibitorsBDB
Biota Scientific Management
Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR.BDB
University of Texas Southwestern Medical Center
Benzobis(imidazolium)-cucurbit[8]uril complexes for binding and sensing aromatic compounds in aqueous solution.BDB
University of Cambridge
Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity.BDB
Johnson & Johnson Pharmaceutical
Second generation of BACE-1 inhibitors part 2: Optimisation of the non-prime side substituent.BDB
Gsk
Synthesis of small molecule inhibitors of the orphan nuclear receptor steroidogenic factor-1 (NR5A1) based on isoquinolinone scaffolds.BDB
Scripps Florida
Potent, exceptionally selective, orally bioavailable inhibitors of TNF-alpha Converting Enzyme (TACE): novel 2-substituted-1H-benzo[d]imidazol-1-yl)methyl)benzamide P1' substituents.BDB
Bristol-Myers Squibb
Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: novel CYP17 inhibitors for the treatment of prostate cancer.BDB
Saarland University