Compile Data Set for Download or QSAR
Report error Found 95 Enz. Inhib. hit(s) with all data for entry = 50039284
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7646(N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50164693(N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(2-chloro-phenyl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50164693(N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(2-chloro-phenyl...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM6619(3-[(9bR)-5-oxo-1H,2H,3H,5H,9bH-benzo[a]pyrrolizin-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM6939(4-hydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-ind...)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7646(N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-4...)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378823(CHEMBL1241849)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378826(CHEMBL1241758)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378552(CHEMBL291324)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378820(CHEMBL1241567)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378552(CHEMBL291324)
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM6939(4-hydroxy-N-({[3-(4-methoxyphenyl)-4-oxo-2H,4H-ind...)
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378823(CHEMBL1241849)
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7262(NSC 705701 | BDBM84528 | alsterpaullone | 9-Nitrop...)
Affinity DataIC50: 15nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM5775(4-butoxy-5-[(2,4,6-trifluorophenyl)carbonyl]-1H-py...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50023871(CHEMBL1207227)
Affinity DataIC50: 22nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50164693(N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(2-chloro-phenyl...)
Affinity DataIC50: 29nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378819(CHEMBL1241566)
Affinity DataIC50: 32nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378822(CHEMBL1241662)
Affinity DataIC50: 33nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7238(cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...)
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7262(NSC 705701 | BDBM84528 | alsterpaullone | 9-Nitrop...)
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7108(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50: 37nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50023871(CHEMBL1207227)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7262(NSC 705701 | BDBM84528 | alsterpaullone | 9-Nitrop...)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50192076(1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazo...)
Affinity DataIC50: 42nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50117488(H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-NH2 | CHEMBL2173...)
Affinity DataIC50: 50nMAssay Description:Binding affinity to Cyclin A by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM5775(4-butoxy-5-[(2,4,6-trifluorophenyl)carbonyl]-1H-py...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378826(CHEMBL1241758)
Affinity DataIC50: 55nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7238(cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...)
Affinity DataIC50: 55nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7238(cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...)
Affinity DataIC50: 65nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50192076(1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazo...)
Affinity DataIC50: 78nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378822(CHEMBL1241662)
Affinity DataIC50: 104nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7108(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50: 114nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50192076(1-{5-[(5-Chloro-indan-2-ylamino)-methyl]-1H-pyrazo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM5711((3S,4R)-2-(2-Chlorophenoxy)-5,7-dihydroxy-8-(3-hyd...)
Affinity DataIC50: 130nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50117488(H-His-Ala-Lys-Arg-Arg-Leu-Ile-Phe-NH2 | CHEMBL2173...)
Affinity DataIC50: 140nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378819(CHEMBL1241566)
Affinity DataIC50: 150nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CDK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 170nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50023871(CHEMBL1207227)
Affinity DataIC50: 200nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378552(CHEMBL291324)
Affinity DataIC50: 230nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378823(CHEMBL1241849)
Affinity DataIC50: 260nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7108(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(naphthalen-2-...)
Affinity DataIC50: 279nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 4(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7238(cid_5289419 | 3-(3H-Imidazol-4-ylmethylene)-5-meth...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CDK4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM6619(3-[(9bR)-5-oxo-1H,2H,3H,5H,9bH-benzo[a]pyrrolizin-...)
Affinity DataIC50: 440nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 450nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50378830(CHEMBL1241136)
Affinity DataIC50: 520nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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