45 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The"Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
Virginia Commonwealth University
Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.
University of Genoa
Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists.
Roche Innovation Center Basel
Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists.
University of Pisa
Optimisation of imidazole compounds as selective TAAR1 agonists: discovery of RO5073012.
F. Hoffmann-La Roche
Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1.
University of California San Francisco
Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class.
Research Triangle Institute
Selective antagonists of mouse trace amine-associated receptor 1 (mTAAR1): discovery of EPPTB (RO5212773).
F. Hoffmann-La Roche
Amiodarone and its putative metabolites fail to activate wild type hTAAR1.
Rti International
Trace amine-associated receptor 1 (TAAR1) is activated by amiodarone metabolites.
University of California San Francisco
Structure-activity correlations for beta-phenethylamines at human trace amine receptor 1.
Rti International
Progress in mechanistically novel treatments for schizophrenia.
Novartis Institutes For Biomedical Research
Trace amine-associated receptor agonists: synthesis and evaluation of thyronamines and related analogues.
University of California San Francisco
Hit-to-Lead Optimization of Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists with a Diphenylmethane-Scaffold: Design, Synthesis, and Biological Study.
University of Pisa
Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine.
Oregon Health & Science University
Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists.
University of Genoa
Substituted benzoxazole and benzofuran compounds as PDE7 inhibitors
Dart Neuroscience
Substituted imidazo[2,1-f][1,2,4]triazines, substituted imidazo[1,2-a]pyridines and substituted imidazo[1,2-b]pyridazines as PI3K-gamma inhibitors
Incyte
Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide
Boehringer Ingelheim International
Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.
University of Colorado School of Medicine
Synthesis and biological evaluation of novel flavanone derivatives as potential antipsychotic agents.
Key Laboratory For Neurodegenerative Diseases of Ministry of Education
Discovery and Characterization of Allosteric WNK Kinase Inhibitors.
Novartis Institutes For Biomedical Research
Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
Albany Molecular Research
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
Abbvie
2,3-dihydro-1H-indene-2-yl urea derivative and pharmaceutical application of same
Toray Industries
Vectorial transport of the peptide CCK-8 by double-transfected MDCKII cells stably expressing the organic anion transporter OATP1B3 (OATP8) and the export pump ABCC2.
German Cancer Research Center
In vitro biological characterization and antiangiogenic effects of PD 166866, a selective inhibitor of the FGF-1 receptor tyrosine kinase.
Parke-Davis Pharmaceutical Research
Affinity of various ligands for GABAA receptors containing alpha 4 beta 3 gamma 2, alpha 4 gamma 2, or alpha 1 beta 3 gamma 2 subunits.
University Clinic For Psychiatry