PMID

Data

Article Title

Organization

Synthesis and structure--activity relationship of new cytotoxic agents targeting human glutathione-S-transferases.

Sapienza University of Rome

Novel oxadiazole analogues derived from ethacrynic acid: design, synthesis, and structure-activity relationships in inhibiting the activity of glutathione S-transferase P1-1 and cancer cell proliferation.

Shandong University

Inhibition of glutathione S-transferase M1 by new gabosine analogues is essential for overcoming cisplatin resistance in lung cancer cells.

Academia Sinica

Compounds structurally related to ellagic acid show improved antiplasmodial activity.

Justus-Liebig-University

Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer.

Jinan University

Furazans in Medicinal Chemistry.

Treventis

Bivalent inhibitors of glutathione S-transferase: the effect of spacer length on isozyme selectivity.

Syntrix Biosytems

Inhibition of glutathione S-transferases by photoactive calix[4]arene α-ketophosphonic acids.

V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of The National Academy of Sciences of Ukraine

Selective inhibition of MCF-7(piGST) breast tumors using glutathione transferase-derived 2-methylene-cycloalkenones.

University of Maryland

Molecular modeling, synthesis, and preliminary biological evaluation of glutathione-S-transferase inhibitors as potential therapeutic agents.

Università

Novel Electrophilic Warhead Targeting a Triple-Negative Breast Cancer Driver in Live Cells Revealed by "Inverse Drug Discovery".

Jinan University

Design, synthesis, and structure-activity relationships of haloenol lactones: site-directed and isozyme-selective glutathione S-transferase inhibitors.

Chinese Academy of Sciences

Discovery of 6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol Derivatives as Glutathione Transferase Inhibitors with Favorable Selectivity and Tolerated Toxicity.

Southeast University

Beta-carbonyl substituted glutathione conjugates as inhibitors Of O. volvulus GST2.

University of Wales

Isozyme-specific glutathione-S-transferase inhibitors: design and synthesis.

Terrapin Technologies

Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example.

Monash University

Fused heterocyclic compounds as orexin receptor modulators

Janssen Pharmaceutica