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8 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of a novel trans-1,4-dioxycyclohexane GPR119 agonist series.EBI
Arena Pharmaceuticals
Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists.EBI
Arena Pharmaceuticals
Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists.EBI
Amgen
Discovery of a second generation agonist of the orphan G-protein coupled receptor GPR119 with an improved profile.EBI
Arena Pharmaceuticals
Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.EBI
Arena Pharmaceuticals
Activation of the G-protein-coupled receptor 119: a conformation-based hypothesis for understanding agonist response.EBI
Pfizer
Discovery of a novel series of GPR119 agonists: Design, synthesis, and biological evaluation of N-(Piperidin-4-yl)-N-(trifluoromethyl)pyrimidin-4-amine derivatives.EBI
Takeda Pharmaceutical
Discovery of a novel series of indolinylpyrimidine-based GPR119 agonists: Elimination of ether-a-go-go-related gene liability using a hydrogen bond acceptor-focused approach.EBI
Takeda Pharmaceutical