10 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3.
University of Oxford
Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable
Sanders Tri-Institutional Therapeutics
Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC.
Nanchang University
Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.
Pfizer
Design, Synthesis, and Biological Evaluations of DOT1L Peptide Mimetics Targeting the Protein-Protein Interactions between DOT1L and MLL-AF9/MLL-ENL.
China Pharmaceutical University
Discovery of Selective Small-Molecule Inhibitors for the ENL YEATS Domain.
Texas A&M University
Structural Insights into Interaction Mechanisms of Alternative Piperazine-urea YEATS Domain Binders in MLLT1.
Goethe-University Frankfurt
Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL).
Goethe-University Frankfurt