PMID

Data

Article Title

Organization

Synthesis and biological evaluation of C-3 aliphatic coumarins as vitamin K antagonists.

Claude Bernard University Lyon 1

Biochemical and pharmacological evaluation of 4-hydroxychromen-2-ones bearing polar C-3 substituents as anticoagulants.

University of Kragujevac

Design of a structure-activity relationship model of vitamin K epoxide reductase (VKORC1) inhibitors combining chemical synthesis of new compounds, enzymatic assays and molecular modelling.

University of Lyon

Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors.

Tunghai University

Determining the necessity of phenyl ring π-character in warfarin.

University of Queensland

2-(Fluoromethyl)-3-phytyl-1,4-naphthoquinone and its 2,3-epoxide. Inhibition of vitamin K epoxide reductase.

Northwestern University

Substituted vitamin K epoxide analogues. New competitive inhibitors and substrates of vitamin K1 epoxide reductase.

Northwestern University

VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy.

Institut National De Recherche Agronomique (Inra)-Vetagro Sup, Veterinary School of Lyon