PMID

Data

Article Title

Organization

Investigation of trypanothione reductase inhibitory activity by 1,3,4-thiadiazolium-2-aminide derivatives and molecular docking studies.

Instituto Oswaldo Cruz

Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis.

Sapienza University of Rome

Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity.

Universidad De Alcal£

Evolution in non-peptide α-helix mimetics on the road to effective protein-protein interaction modulators.

IQM-CSIC

Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase.

Universidad De Alcal£

Efficient Dimerization Disruption of

Instituto De Qu£Mica M£Dica (Iqm-Csic)

Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability.

Instituto De Qu£Mica M£Dica (Iqm-Csic)

Improved proteolytic stability and potent activity against Leishmania infantum trypanothione reductase of α/β-peptide foldamers conjugated to cell-penetrating peptides.

Universidad De Alcal£

First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity

Instituto De Qu£Mica M£Dica (Iqm-Csic)