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32 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthetic strategy for increasing solubility of potential FLT3 inhibitor thieno[2,3-d]pyrimidine derivatives through structural modifications at the CEBI
Yonsei University
5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity.EBI
Yonsei University
Structural modifications at the 6-position of thieno[2,3-d]pyrimidines and their effects on potency at FLT3 for treatment of acute myeloid leukemia.EBI
Yonsei University
Identification of small-molecule compounds targeting the dishevelled PDZ domain by virtual screening and binding studies.EBI
Yonsei University
Novel N-acyl-carbazole derivatives as 5-HT7R antagonists.EBI
Yonsei University
Discovery of 2-aryloxy-4-amino-quinazoline derivatives as novel protease-activated receptor 2 (PAR2) antagonists.EBI
Yonsei University
Synthesis and biological evaluation of aryl isoxazole derivatives as metabotropic glutamate receptor 1 antagonists: a potential treatment for neuropathic pain.EBI
Yonsei University
Discovery of Orally Available Runt-Related Transcription Factor 3 (RUNX3) Modulators for Anticancer Chemotherapy by Epigenetic Activation and Protein Stabilization.EBI
Yonsei University
Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression.EBI
Yonsei University
Novel thienopyrimidinones as mGluR1 antagonists.EBI
Yonsei University
Synthesis and biological evaluation of novel thieno[2,3-d]pyrimidine-based FLT3 inhibitors as anti-leukemic agents.EBI
Yonsei University
Structure-based optimization and biological evaluation of trisubstituted pyrazole as a core structure of potent ROS1 kinase inhibitors.EBI
Yonsei University
Enantioselective induction of SIRT1 gene by syringaresinol from Panax ginseng berry and Acanthopanax senticosus Harms stem.EBI
Yonsei University
Development of a novel class of mitochondrial ubiquinol-cytochrome c reductase binding protein (UQCRB) modulators as promising antiangiogenic leads.EBI
Yonsei University
Discovery of (E)-5-(benzylideneamino)-1H-benzo[d]imidazol-2(3H)-one derivatives as inhibitors for PTK6.EBI
Yonsei University
Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKß inhibitors.EBI
Yonsei University
3-Amino-N-adamantyl-3-methylbutanamide derivatives as 11ß-hydroxysteroid dehydrogenase 1 inhibitor.EBI
Yonsei University
Design, synthesis, and discovery of stilbene derivatives based on lithospermic acid B as potent protein tyrosine phosphatase 1B inhibitors.EBI
Yonsei University
Structure and property based design, synthesis and biological evaluation of¿-lactam based HDAC inhibitors.EBI
Yonsei University
Structure based optimization of chromen-based TNF-a converting enzyme (TACE) inhibitors on S1' pocket and their quantitative structure-activity relationship (QSAR) study.EBI
Yonsei University
Chromen-based TNF-alpha converting enzyme (TACE) inhibitors: design, synthesis, and biological evaluation.EBI
Yonsei University
Synthetic Strategies for Improving Solubility: Optimization of Novel Pyrazolo[1,5-EBI
Yonsei University
Development of Novel VEGFR2 Inhibitors Originating from Natural Product Analogues with Antiangiogenic Impact.EBI
Yonsei University
X-ray Crystal Structure-Guided Design and Optimization of 7EBI
Yonsei University
Rational design of an indolebutanoic acid derivative as a novel aldose reductase inhibitor based on docking and 3D QSAR studies of phenethylamine derivatives.EBI
Yonsei University
Synthesis of novel 1H-Pyrazolo[3,4-b]pyridine derivatives as DYRK 1A/1B inhibitors.EBI
Yonsei University
The food-grade antimicrobial xanthorrhizol targets the enoyl-ACP reductase (FabI) in Escherichia coli.EBI
Yonsei University
Design, synthesis, and biological evaluation of novel pyrrolo[1,2-a]pyrazine derivatives.EBI
Yonsei University
Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors.EBI
Yonsei University
Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson's disease therapy.EBI
Yonsei University
Pharmaceutical compositionBDB
Eisai R&D Management