PMID

Data

Article Title

Organization

Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043.

University of Notre Dame

O-phenyl carbamate and phenyl urea thiiranes as selective matrix metalloproteinase-2 inhibitors that cross the blood-brain barrier.

University of Notre Dame

On the inhibition of histone deacetylase 8.

University of Notre Dame

Design and synthesis of a siderophore conjugate as a potent PSMA inhibitor and potential diagnostic agent for prostate cancer.

University of Notre Dame

Selective water-soluble gelatinase inhibitor prodrugs.

University of Notre Dame

Recent advances toward the development of Hsp90 C-terminal inhibitors.

University of Notre Dame

On the function of the 14 A long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors.

University of Notre Dame

Intracellular fluorescence competition assay for inhibitor engagement of histone deacetylase.

University of Notre Dame

Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.

University of Notre Dame

Validation of Matrix Metalloproteinase-9 (MMP-9) as a Novel Target for Treatment of Diabetic Foot Ulcers in Humans and Discovery of a Potent and Selective Small-Molecule MMP-9 Inhibitor That Accelerates Healing.

University of Notre Dame

In Search of Selectivity in Inhibition of ADAM10.

University of Notre Dame

Discovery of Mechanism-Based Inactivators for Human Pancreatic Carboxypeptidase A from a Focused Synthetic Library.

University of Notre Dame

Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases.

University of Notre Dame

Naphtho and benzo analogues of the kappa opioid agonist trans-(+/-)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] benzeneacetamide.

University of Notre Dame

Inhibitors of glutaminyl cyclase

Probiodrug

Nitrogen-containing heteroaryl derivatives

Hoffmann-La Roche

Discovery of a potent and selective aurora kinase inhibitor.

Sunesis Pharmaceuticals

Structure-based design of HIV protease inhibitors: 4-hydroxycoumarins and 4-hydroxy-2-pyrones as non-peptidic inhibitors.

Upjohn