Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50039186
TargetHistone deacetylase 1(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50: 1nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 11nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 25nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 26nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 120nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 240nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 2(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 260nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19130(CHEMBL99 | (2E,4E,6R)-7-[4-(dimethylamino)phenyl]-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50: 300nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 630nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM22449(N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-1,3-oxazol-2-yl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50238632((6S,9S,12S,14aR)-6-((S)-sec-Butyl)-9-(1-methoxy-1H...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 8(Human)
University of Notre Dame

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed