PMID

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Article Title

Organization

Structure-activity relationships and pharmacokinetic analysis for a series of potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitors.

Parke-Davis Pharmaceutical Research

Novel farnesol and geranylgeraniol analogues: A potential new class of anticancer agents directed against protein prenylation.

Parke-Davis Pharmaceutical Research

Inhibitors of acyl-CoA:cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 8. Incorporation of amide or amine functionalities into a series of disubstituted ureas and carbamates. Effects on ACAT inhibition in vitro and efficacy in vivo.

Parke-Davis Pharmaceutical Research

Identification and characterization of m4 selective muscarinic antagonists.

Parke-Davis Pharmaceutical Research

Parallel synthesis of a series of subtype-selective NMDA receptor antagonists.

Parke-Davis Pharmaceutical Research

Structure-activity relationship at the proximal phenyl group in a series of non-peptidyl N-type calcium channel antagonists.

Parke-Davis Pharmaceutical Research

Isoindolinone enantiomers having affinity for the dopamine D4 receptor.

Parke-Davis Pharmaceutical Research

Novel nonpeptide CCK-B antagonists: design and development of quinazolinone derivatives as potent, selective, and orally active CCK-B antagonists.

Parke-Davis Pharmaceutical Research

Structure-activity relationships for a novel series of pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors.

Parke-Davis Pharmaceutical Research

The discovery and structure-activity relationships of 1,2,3,6-tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine autoreceptor agonists and potential antipsychotic agents.

Parke-Davis Pharmaceutical Research

Mammalian and bacterial nitric oxide synthase inhibitors

Northwestern University

Heterocyclic derivates

Kalvista Pharmaceuticals

Pyrimidine-2,4-diamine derivative and anticancer pharmaceutical composition comprising same as effective ingredient

Korea Research Institute of Chemical Technology

8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and thier use as pharmaceutical compositions

Boehringer Ingelheim International

Substituted pyridobenzodiazepinone-derivatives and use thereof

Bayer Pharma Aktiengesellschaft

Inhibitors of bruton's tyrosine kinase

Hoffmann-La Roche

Dihydropyrido pyrimidine compounds as autotaxin inhibitors

Eli Lilly

Pyrrolidino heterocycles

Hoffmann-La Roche

Cannabinoid-2 agonists

Allergan

Small molecule myristate inhibitors of Bcr-abl and methods of use

Dana-Farber Cancer Institute

Pteridine ketone derivative and applications thereof as EGFR, BLK, and FLT3 inhibitor

East China University of Science and Technology

Inhibitors of PI3K-delta and methods of their use and manufacture

Exelixis

Combinations comprising PDE 2 inhibitors such as 1-aryl-4-methyl-[1,2,4]triazolo-[4,3-A]]quinoxaline compounds and PDE 10 inhibitors for use in the treatment of neurological of metabolic disorders

Janssen Pharmaceutica

BET bromodomain inhibitors and therapeutic methods using the same

The Regents of The University of Michigan

Anti-fibrotic pyridinones

Intermune

Benzoxazinone derivatives for treatment of skin diseases

Sixera Pharma

Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53.

Max Planck Institute

Macrocycle and composition comprising thereof

Shenzhen Targetrx