Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50007152
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3450(1-[6-(2,6-dichlorophenyl)-2-{[4-(diethylamino)buty...)
Affinity DataIC50: 23nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3465(CHEMBL57347 | 3-tert-butyl-1-[6-(2,6-dichloropheny...)
Affinity DataIC50: 31nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3451(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[4-(diet...)
Affinity DataIC50: 44nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3431(CHEMBL299026 | 3-tert-butyl-1-[6-(2,6-dichlorophen...)
Affinity DataIC50: 73nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059137(1-[2-Amino-6-(2,6-dichloro-phenyl)-pyrido[2,3-d]py...)
Affinity DataIC50: 77nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3433(6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...)
Affinity DataIC50: 110nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3465(CHEMBL57347 | 3-tert-butyl-1-[6-(2,6-dichloropheny...)
Affinity DataIC50: 150nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3428(CHEMBL57366 | 1-[2-amino-6-(2,6-dichlorophenyl)pyr...)
Affinity DataIC50: 220nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3451(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[4-(diet...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3428(CHEMBL57366 | 1-[2-amino-6-(2,6-dichlorophenyl)pyr...)
Affinity DataIC50: 450nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3433(6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...)
Affinity DataIC50: 610nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3450(1-[6-(2,6-dichlorophenyl)-2-{[4-(diethylamino)buty...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059137(1-[2-Amino-6-(2,6-dichloro-phenyl)-pyrido[2,3-d]py...)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059138(1-tert-Butyl-3-[2-[3-(4-methyl-piperazin-1-yl)-pro...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM4823(1-{2-amino-6-phenylpyrido[2,3-d]pyrimidin-7-yl}-3-...)
Affinity DataIC50: 5.53E+3nMAssay Description:Inhibition of epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3431(CHEMBL299026 | 3-tert-butyl-1-[6-(2,6-dichlorophen...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3441(1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...)
Affinity DataIC50: 6.68E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059138(1-tert-Butyl-3-[2-[3-(4-methyl-piperazin-1-yl)-pro...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3431(CHEMBL299026 | 3-tert-butyl-1-[6-(2,6-dichlorophen...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3441(1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3428(CHEMBL57366 | 1-[2-amino-6-(2,6-dichlorophenyl)pyr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3433(6-arylpyrido[2,3-d]pyrimidine deriv. 15 | CHEMBL57...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM4823(1-{2-amino-6-phenylpyrido[2,3-d]pyrimidin-7-yl}-3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3451(3-tert-butyl-1-[6-(2,6-dichlorophenyl)-2-{[4-(diet...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059138(1-tert-Butyl-3-[2-[3-(4-methyl-piperazin-1-yl)-pro...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3443(6-arylpyrido[2,3-d]pyrimidine deriv. 25 | PD 16686...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3443(6-arylpyrido[2,3-d]pyrimidine deriv. 25 | PD 16686...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3443(6-arylpyrido[2,3-d]pyrimidine deriv. 25 | PD 16686...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Epidermal growth factor receptor (EGFr) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50059137(1-[2-Amino-6-(2,6-dichloro-phenyl)-pyrido[2,3-d]py...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM4823(1-{2-amino-6-phenylpyrido[2,3-d]pyrimidin-7-yl}-3-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3450(1-[6-(2,6-dichlorophenyl)-2-{[4-(diethylamino)buty...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3441(1-[2-amino-6-(2,3,5,6-tetramethylphenyl)pyrido[2,3...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of C-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin receptor(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM3465(CHEMBL57347 | 3-tert-butyl-1-[6-(2,6-dichloropheny...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of insulin receptor (InsR) tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed