19 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK).

Novartis Institute For Biomedical Research
Structure-based design and optimization of potent inhibitors of the adenoviral protease.

Novartis Institute For Biomedical Research
Imidazo[4,5-c]quinolines as inhibitors of the PI3K/PKB-pathway.

Novartis Institute For Biomedical Research
Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.

Novartis Institute For Biomedical Research
1-Aminomethylisoquinoline-4-carboxylates as novel dipeptidylpeptidase IV inhibitors.

Novartis Institute For Biomedical Research
Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase.

Novartis Institute For Biomedical Research
A novel Pd-catalyzed cyclization reaction of ureas for the synthesis of dihydroquinazolinone p38 kinase inhibitors.

Novartis Institute For Biomedical Research
1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.

Novartis Institute For Biomedical Research
1,4-Diazepane-2-ones as novel inhibitors of LFA-1.

Novartis Institute For Biomedical Research
Synthesis and biological activity of potent heterocyclic thiol-based inhibitors of endothelin-converting enzyme-1.

Novartis Institute For Biomedical Research
Design and synthesis of potent and selective inhibitors of integrin VLA-4.

Novartis Institute For Biomedical Research
Isoindolines: a new series of potent and selective endothelin-A receptor antagonists.

Novartis Institute For Biomedical Research
Synthesis and biological activity of novel potent endothelin-converting enzyme-1 inhibitors.

Novartis Institute For Biomedical Research
Design and synthesis of potent thiol-based inhibitors of endothelin converting enzyme-1.

Novartis Institute For Biomedical Research
Scaffold Morphing Identifies 3-Pyridyl Azetidine Ureas as Inhibitors of Nicotinamide Phosphoribosyltransferase (NAMPT).

Novartis Institute For Biomedical Research
N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824).

Novartis Institute For Biomedical Research
Secondary amides of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.

Novartis Institute For Biomedical Research
Anilides of (R)-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.

Novartis Institute For Biomedical Research