41 articles for thisTarget
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3D-QSAR studies on thieno[3,2-d]pyrimidines as phosphodiesterase IV inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
Discovery of 4-sulfamoyl-phenyl-ß-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
Design and synthesis of novel Y-shaped barbituric acid derivatives as PPAR¿ activators.
National Institute of Pharmaceutical Education and Research (NIPER)
Switch in Site of Inhibition: A Strategy for Structure-Based Discovery of Human Topoisomerase IIa Catalytic Inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
Biological evaluation and structural insights for design of subtype-selective peroxisome proliferator activated receptor-a (PPAR-a) agonists.
National Institute of Pharmaceutical Education and Research (NIPER)
2-(2-Arylphenyl)benzoxazole As a Novel Anti-Inflammatory Scaffold: Synthesis and Biological Evaluation.
National Institute of Pharmaceutical Education and Research (NIPER)
Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents.
National Institute of Pharmaceutical Education and Research (NIPER)
Three-dimensional quantitative structure (3-D QSAR) activity relationship studies on imidazolyl and N-pyrrolyl heptenoates as 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) inhibitors by comparative molecular similarity indices analysis (CoMSIA).
National Institute of Pharmaceutical Education and Research (NIPER)
N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIa and induce apoptosis in G1/S phase.
National Institute of Pharmaceutical Education and Research (NIPER)
Synthesis, biological evaluation and molecular docking studies of stellatin derivatives as cyclooxygenase (COX-1, COX-2) inhibitors and anti-inflammatory agents.
National Institute of Pharmaceutical Education and Research (NIPER)
Discovery of dual binding site acetylcholinesterase inhibitors identified by pharmacophore modeling and sequential virtual screening techniques.
National Institute of Pharmaceutical Education and Research (NIPER)
QSAR studies on CCR2 antagonists with chiral sensitive hologram descriptors.
National Institute of Pharmaceutical Education and Research (NIPER)
Probing the structural and topological requirements for CCR2 antagonism: holographic QSAR for indolopiperidine derivatives.
National Institute of Pharmaceutical Education and Research (NIPER)
Development of trisubstituted thiophene-3-arboxamide selenide derivatives as novel EGFR kinase inhibitors with cytotoxic activity.
National Institute of Pharmaceutical Education and Research (NIPER)
New structural classes of antimalarials.
National Institute of Pharmaceutical Education and Research (NIPER)
Synthesis and pharmacological evaluation of 1,3-diaryl substituted pyrazole based (thio)urea derivatives as potent antimicrobial agents against multi-drug resistant
National Institute of Pharmaceutical Education and Research (NIPER)
Identification of leads for antiproliferative activity on MDA-MB-435 human breast cancer cells through pharmacophore and CYP1A1-mediated metabolism.
National Institute of Pharmaceutical Education and Research (NIPER)
Non-carbohydrate strategies to inhibit lectin proteins with special emphasis on galectins.
National Institute of Pharmaceutical Education and Research (NIPER)
Anticancer potential of spirocompounds in medicinal chemistry: A pentennial expedition.
National Institute of Pharmaceutical Education and Research (NIPER)
FabI (enoyl acyl carrier protein reductase) - A potential broad spectrum therapeutic target and its inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
Fused-azepinones: Emerging scaffolds of medicinal importance.
National Institute of Pharmaceutical Education and Research (NIPER)
Structural insights of oxindole based kinase inhibitors as anticancer agents: Recent advances.
National Institute of Pharmaceutical Education and Research (NIPER)
Design, synthesis of DNA-interactive 4-thiazolidinone-based indolo-/pyrroloazepinone conjugates as potential cytotoxic and topoisomerase I inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases.
National Institute of Pharmaceutical Education and Research (NIPER)
Organocatalyzed umpolung addition for synthesis of heterocyclic-fused arylidene-imidazolones as anticancer agents.
National Institute of Pharmaceutical Education and Research (NIPER)
Synthesis of a new series of quinoline/pyridine indole-3-sulfonamide hybrids as selective carbonic anhydrase IX inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
Paradigm shift of "classical" HDAC inhibitors to "hybrid" HDAC inhibitors in therapeutic interventions.
National Institute of Pharmaceutical Education and Research (NIPER)
Design, synthesis and in-vitro evaluation of fluorinated triazoles as multi-target directed ligands for Alzheimer disease.
National Institute of Pharmaceutical Education and Research (NIPER)
Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect.
National Institute of Pharmaceutical Education and Research (NIPER)
Synthesis and biological evaluation of novel 4,7-disubstituted coumarins as selective tumor-associated carbonic anhydrase IX and XII inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation.
National Institute of Pharmaceutical Education and Research (NIPER)
3-Functionalised benzenesulphonamide based 1,3,4-oxadiazoles as selective carbonic anhydrase XIII inhibitors: Design, synthesis and biological evaluation.
National Institute of Pharmaceutical Education and Research (NIPER)
Synthesis and exploration of 2-morpholino-4-phenylthiazol-5-yl acrylamide derivatives for their effects against carbonic anhydrase I, II, IX and XII isoforms as a non-sulfonamide class of inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
Cyclic enaminone as new chemotype for selective cyclooxygenase-2 inhibitory, anti-inflammatory, and analgesic activities.
National Institute of Pharmaceutical Education and Research (NIPER)
Cinnamamide: An insight into the pharmacological advances and structure-activity relationships.
National Institute of Pharmaceutical Education and Research (NIPER)
Rotenoids from Boerhaavia diffusa as potential anti-inflammatory agents.
National Institute of Pharmaceutical Education and Research (NIPER)
Quantitative structure activity relationship studies on thiourea analogues as influenza virus neuraminidase inhibitors.
National Institute of Pharmaceutical Education and Research (NIPER)
Glycogen synthase kinase-3 and its inhibitors: Potential target for various therapeutic conditions.
National Institute of Pharmaceutical Education and Research (NIPER)