Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50008077
TargetAmine oxidase [flavin-containing] B(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50341135(N-p-Coumaroyl serotonin | CHEMBL1760547)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of recombinant human MAOB using kynuramine as substrate preincubated with substrate for 10 mins followed by enzyme addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50142954(4-[(E)-2-({1-[2,4-Dichloro-3-(4-imidazol-1-yl-2-me...)
Affinity DataIC50: 0.260nMAssay Description:Displacement of [3H]bradykinin from human recombinant bradykinin B2 receptor expressed in CHO cells incubated for 2 hrs by liquid scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Guinea pig)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50067290(5-{2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-yloxy...)
Affinity DataIC50: 0.460nMAssay Description:Displacement of [3H]BK from Bradykinin B2 Receptor in guinea pig ileum by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515481(CHEMBL4439680)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of VEGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515483(CHEMBL4466350)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of VEGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515481(CHEMBL4439680)
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515483(CHEMBL4466350)
Affinity DataIC50: 9nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetP-selectin(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50100507(3-(4-{4-[4-(2-Carboxy-vinyl)-phenyl]-5-[4-(2-hexad...)
Affinity DataIC50: 300nMAssay Description:Inhibition of P-selectin (unknown origin) incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515482(CHEMBL4453659)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50429762(N-(2-Methoxyphenyl)Cinnamamide | CHEMBL2336355)
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of recombinant His-tagged human EGFR (645 to 1186 residues) cytoplasmic domain expressed in baculovirus infected Sf9 cells incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50429757(N-(2-Fluorophenyl)Cinnamamide | CHEMBL1998736)
Affinity DataIC50: 7.37E+3nMAssay Description:Inhibition of recombinant His-tagged human EGFR (645 to 1186 residues) cytoplasmic domain expressed in baculovirus infected Sf9 cells incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetP-selectin(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50100506(3-(4-{5-[4-(2-Hexadecylcarbamoyl-vinyl)-phenyl]-1H...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of P-selectin (unknown origin) incubated for 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515484(CHEMBL4588220)
Affinity DataIC50: 8.67E+4nMAssay Description:Inhibition of recombinant human BACE 1 using Rh-EVNL-DAEFK-Quencher as substrate incubated for 60 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed