PMID

Data

Article Title

Organization

Synthesis and cardiotonic activity of novel biimidazoles.

Merrell Dow Research Institute

Graphics computer-aided receptor mapping as a predictive tool for drug design: development of potent, selective, and stereospecific ligands for the 5-HT1A receptor.

Merrell Dow Research Institute

Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a model for this receptor site.

Merrell Dow Research Institute

4',5'-unsaturated 5'-halogenated nucleosides. Mechanism-based and competitive inhibitors of S-adenosyl-L-homocysteine hydrolase.

Merrell Dow Research Institute

Polyamine analogues with antitumor activity.

Merrell Dow Research Institute

A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors.

Merrell Dow Research Institute

(R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex.

Merrell Dow Research Institute

Alpha-diketone and alpha-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinases.

Merrell Dow Research Institute

Benzo[1,2-c:5,4-c']dipyrazoles: non-xanthine adenosine antagonists.

Merrell Dow Research Institute

2,2-Difluoro-5-hexyne-1,4-diamine: a potent enzyme-activated inhibitor of ornithine decarboxylase.

Merrell Dow Research Institute

1-(Thienylalkyl)imidazole-2(3H)-thiones as potent competitive inhibitors of dopamine beta-hydroxylase.

Merrell Dow Research Institute

Synthesis of peptidyl fluoromethyl ketones and peptidyl alpha-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G.

Merrell Dow Research Institute

Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy.

University of Michigan