Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 3310
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

LigandPNGBDBM31197(CHEMBL211045 | Nutlin-3 | med.21724, Compound 186)
Affinity DataKi:  36nM ΔG°:  -42.2kJ/molepH: 7.5 T: 2°CAssay Description:The dose-dependent binding experiments were carried out with serial dilutions of the tested compounds in DMSO. A 5 ul sample of the tested samples an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

LigandPNGBDBM31196(spiro-oxindole, 1)
Affinity DataKi:  86nM ΔG°:  -40.1kJ/molepH: 7.5 T: 2°CAssay Description:The dose-dependent binding experiments were carried out with serial dilutions of the tested compounds in DMSO. A 5 ul sample of the tested samples an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

LigandPNGBDBM31206(NSC 66811)
Affinity DataKi:  120nM ΔG°:  -39.2kJ/molepH: 7.5 T: 2°CAssay Description:The dose-dependent binding experiments were carried out with serial dilutions of the tested compounds in DMSO. A 5 ul sample of the tested samples an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2009
Entry Details Article
PubMed