PMID

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Doxifluridine-conjugated 2-5A analog shows strong RNase L activation ability and tumor suppressive effect.

Gifu University

Potent small molecule mouse CD22-inhibitors: exploring the interaction of the residue at C-2 of sialic acid scaffold.

Gifu University

Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase.

Gifu University

Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.

Gifu University

CD22-antagonists with nanomolar potency: the synergistic effect of hydrophobic groups at C-2 and C-9 of sialic acid scaffold.

Gifu University

Variety of antiprion compounds discovered through an in silico screen based on cellular-form prion protein structure: Correlation between antiprion activity and binding affinity.

Gifu University

5'-O-Dephosphorylated 2',5'-oligoadenylate (2-5A) with 8-methyladenosine at the 2'-terminus activates human RNase L.

Gifu University

Human sialidase inhibitors: design, synthesis, and biological evaluation of 4-acetamido-5-acylamido-2-fluoro benzoic acids.

Gifu University

Design, synthesis, and structure-affinity relationships of novel series of sialosides as CD22-specific inhibitors.

Gifu University

Synthesis of 3',4'-epoxynoraristeromycin analogs for molecular labeling probe of S-adenosyl-l-homocysteine hydrolase.

Gifu University

Design, synthesis, and biological evaluation of human sialidase inhibitors. Part 1: selective inhibitors of lysosomal sialidase (NEU1).

Gifu University

A lead compound for the development of ABA 8'-hydroxylase inhibitors.

Gifu University

Development of flavonoid probes and the binding mode of the target protein and quercetin derivatives.

Gifu University

Synthesis of 2-fluoronoraristeromycin and its inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.

Gifu University

Sulfonamide antibiotics inhibit RNAi by binding to human Argonaute protein 2 PAZ.

Gifu University

2-Methyladenosine-Substituted 2',5'-oligoadenylates: conformations, 2-5A binding and catalytic activities with human ribonuclease L.

Gifu University

9-[(2'S,3'S)-3'-formyl-2',3'-dihydroxypropyl]adenine: a facile affinity-labeling probe of human S-adenosyl-L-homocysteine hydrolase.

Gifu University

Comparative analysis of stilbene and benzofuran neolignan derivatives as acetylcholinesterase inhibitors with neuroprotective and anti-inflammatory activities.

Gifu University

Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations.

Gifu University

Unique neonicotinoid binding conformations conferring selective receptor interactions.

Gifu University

Furan-2,5-dimethylene-tethered bis-imidacloprid insecticide conferring high potency.

Gifu University