PMID

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Development of first lead structures for phosphoinositide 3-kinase-C2¿ inhibitors.

Eberhard Karls University Tuebingen

Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase.

Eberhard Karls University Tuebingen

Design, synthesis, and biological evaluation of novel Tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: focus on optimized interactions with the enzyme's surface-exposed front region.

Eberhard Karls University Tuebingen

Identification of 2-mercaptohexanoic acids as dual inhibitors of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1.

Eberhard Karls University Tuebingen

Discovery of benzo[g]indol-3-carboxylates as potent inhibitors of microsomal prostaglandin E(2) synthase-1.

Eberhard Karls University Tuebingen

Arylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) or as dual inhibitors of mPGES-1 and 5-lipoxygenase (5-LOX).

Eberhard Karls University Tuebingen

Arylpiperazine derivatives and methods of utilizing same

Reviva Pharmaceuticals

Pentachlorophenol hydroxylase, a poorly functioning enzyme required for degradation of pentachlorophenol by Sphingobium chlorophenolicum.

University of Colorado Boulder