PMID

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Article Title

Organization

Role of Reactive Oxygen Species (ROS) in Therapeutics and Drug Resistance in Cancer and Bacteria.

Case Western Reserve University

Identification of cryptotanshinone as an inhibitor of oncogenic protein tyrosine phosphatase SHP2 (PTPN11).

Case Western Reserve University

Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase.

Case Western Reserve University

In Vitro Activation of Cytochrome P450 46A1 (CYP46A1) by Efavirenz-Related Compounds.

Case Western Reserve University

Identification of Non-nucleoside Human Ribonucleotide Reductase Modulators.

Case Western Reserve University

Dibenzothiazoles as novel amyloid-imaging agents.

Case Western Reserve University

Modification of the enkephalin"message" with an artificial polycationic C-terminus.

Case Western Reserve University

Structure-Guided Synthesis and Mechanistic Studies Reveal Sweetspots on Naphthyl Salicyl Hydrazone Scaffold as Non-Nucleosidic Competitive, Reversible Inhibitors of Human Ribonucleotide Reductase.

Case Western Reserve University

Compounds for Disease Treatment

Duke University

HSD17B13 INHIBITORS AND USES THEREOF

Fl2022-001

GSK-3 inhibitors

Bristol-Myers Squibb

Pharmaceutical composition for treating FLT3 mutation-positive cancer, mutant FLT3 inhibitor and uses thereof

Fujifilm

Benzimidazol-2-amines as MIDH1 inhibitors

Bayer Pharma Aktiengesellschaft

Tetrahydro-pyrimidoazepines as modulators of TRPV1

Janssen Pharmaceutica

Isonicotinohydrazones as inhibitors of alkaline phosphatase and ecto-5'-nucleotidase.

Quaid-I-Azam University

Compounds and compositions for inhibiting the activity of ABL1, ABL2 and BCR-ABL1

Novartis

Macrolides and their use

Basilea Pharmaceutica

Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use

F. Hoffmann-La Roche

Mixed cocaine agonist/antagonist properties of (+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidine-3alpha-carboxylate, a piperidine-based analog of cocaine.

Georgetown University

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.

The Scripps Research Institute

Identification of RIP1 kinase as a specific cellular target of necrostatins.

Tufts University

Correlating solution binding and ESI-MS stabilities by incorporating solvation effects in a confined cucurbit[8]uril system.

University of Cambridge

Thermodynamics of the molecular and chiral recognition of cycloalkanols and camphor by modified beta-cyclodextrins possessing simple aromatic tethers.

Nankai University

Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists.

Ono Pharmaceutical

3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3.

Wyeth Research

Rhodanine derivatives as selective protease inhibitors against bacterial toxins.

Burnham Institute For Medical Research