Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 3472
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35211(pyrimidoindolone, 19b)
Affinity DatapH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35210(pyrimidoindolone, 19a)
Affinity DatapH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35221(pyrimidoindolone, 25b)
Affinity DataIC50: 1.29nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35223(pyrimidoindolone, 25d)
Affinity DataIC50: 2.32nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35202(pyrimidoindolone, 11k)
Affinity DataIC50: 2.40nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35220(pyrimidoindolone, 25a)
Affinity DataIC50: 3.30nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35203(pyrimidoindolone, 11l)
Affinity DataIC50: 4.43nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35206(pyrimidoindolone, 14a)
Affinity DataIC50: 4.99nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM19730(3,3-dimethyl-8-{[(2S)-2-(phenoxymethyl)pyrrolidine...)
Affinity DataIC50: 7nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35204(pyrimidoindolone, 11m)
Affinity DataIC50: 7.18nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35199(pyrimidoindolone, 11h)
Affinity DataIC50: 7.81nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35205(pyrimidoindolone, 11n)
Affinity DataIC50: 10.1nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35200(pyrimidoindolone, 11i)
Affinity DataIC50: 10.2nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35192(pyrimidoindolone, 11a)
Affinity DataIC50: 10.8nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35201(pyrimidoindolone, 11j)
Affinity DataIC50: 12.6nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35224(pyrimidoindolone, 25e)
Affinity DataIC50: 13.6nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35193(pyrimidoindolone, 11b)
Affinity DataIC50: 13.8nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35207(pyrimidoindolone, 14b)
Affinity DataIC50: 14.3nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35222(pyrimidoindolone, 25c)
Affinity DataIC50: 14.8nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35197(pyrimidoindolone, 11f)
Affinity DataIC50: 23nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35225(pyrimidoindolone, 25f)
Affinity DataIC50: 24.6nMT: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35195(pyrimidoindolone, 11d)
Affinity DataIC50: 30nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35194(pyrimidoindolone, 11c)
Affinity DataIC50: 37nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35208(pyrimidoindolone, 14c)
Affinity DataIC50: 43.6nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35209(pyrimidoindolone, 14d)
Affinity DataIC50: 59nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35196(pyrimidoindolone, 11e)
Affinity DataIC50: 81nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35198(pyrimidoindolone, 11g)
Affinity DataIC50: 82nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35213(pyrimidoindolone, 22b)
Affinity DataIC50: 148nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35214(pyrimidoindolone, 22c)
Affinity DataIC50: 191nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35215(pyrimidoindolone, 22d)
Affinity DataIC50: 350nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35212(pyrimidoindolone, 22a)
Affinity DataIC50: 364nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35216(pyrimidoindolone, 22e)
Affinity DataIC50: 1.34E+3nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35217(pyrimidoindolone, 22f)
Affinity DataIC50: 1.50E+3nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35219(pyrimidoindolone, 22h)
Affinity DataIC50: 2.39E+3nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Wyeth Research

LigandPNGBDBM35218(pyrimidoindolone, 22g)
Affinity DataIC50: 2.52E+3nMpH: 7.2 T: 2°CAssay Description:Caspase-3 was assayed at 23 deg C (room temp) in 96-well plates using the internally quenched tetrapeptide substrate. Enzymatic cleavage between the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2009
Entry Details Article
PubMed