PMID

Data

Article Title

Organization

3D-QSAR and QSSR studies of 3,8-diazabicyclo[4.2.0]octane derivatives as neuronal nicotinic acetylcholine receptors by comparative molecular field analysis (CoMFA).

Burnham Institute For Medical Research

An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and protein-tyrosine phosphatase activity.

Burnham Institute For Medical Research

Pyrrolotriazine compounds as tam inhibitors

Incyte

Pyrazole compound

Sumitomo Dainippon Pharma

Macrocyclic compounds for inhibition of inhibitors of apoptosis

Ensemble Therapeutics

Inhibitors of the renal outer medullary potassium channel

Merck Sharp & Dohme

Substituted pyrido[4,3-d]pyrimidines as Wee-1 inhibitors

Almac Discovery

Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors

H. Lundbeck

The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs.

Merck Frosst Centre For Therapeutic Research

The structural basis for the selectivity of benzotriazole inhibitors of PTP1B.

Merck Research Laboratories

Structure-based design of nonpeptide inhibitors of interleukin-1beta converting enzyme (ICE, caspase-1).

Pfizer

Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR.

Vernalis (R&D)

Discovery of huperzine A-tacrine hybrids as potent inhibitors of human cholinesterases targeting their midgorge recognition sites.

Universita Di Siena

Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

Boehringer Ingelheim Pharmaceuticals