PMID

Data

Article Title

Organization

Enriching screening libraries with bioactive fragment space.

Beijing University of Technology

Discovery of new [1,4]dioxino[2,3-f]quinazoline-based inhibitors of EGFR including the T790M/L858R mutant.

Beijing University of Technology

Novel morpholin-3-one fused quinazoline derivatives as EGFR tyrosine kinase inhibitors.

Beijing University of Technology

Design, synthesis, and biological activity of phenyl-pyrazole derivatives as BCR-ABL kinase inhibitors.

Beijing University of Technology

Design and synthesis of N-methylpyrimidone derivatives as HIV-1 integrase inhibitors.

Beijing University of Technology

Three-dimensional QSAR analyses of 1,3,4-trisubstituted pyrrolidine-based CCR5 receptor inhibitors.

Beijing University of Technology

Synthesis and biological evaluation of

Beijing University of Technology

Development of pyrazolo[3,4-d]pyrimidin-4-one scaffold as novel CDK2 inhibitors: Design, synthesis, and biological evaluation.

Beijing University of Technology

The optimization and characterization of functionalized sulfonamides derived from sulfaphenazole against Mycobacterium tuberculosis with reduced CYP 2C9 inhibition.

Beijing University of Technology

Design, synthesis, and biological activity of 4-(imidazo[1,2-b]pyridazin-3-yl)-1H-pyrazol-1-yl-phenylbenzamide derivatives as BCR-ABL kinase inhibitors.

Beijing University of Technology

Discovery of Dioxino[2,3-f]quinazoline derivative VEGFR-2 inhibitors exerting significant antipro-liferative activity in HUVECs and mice.

Beijing University of Technology

Design and synthesis of novel β-diketo derivatives as HIV-1 integrase inhibitors.

Beijing University of Technology

Synthesis of polyhydroxylated aromatics having amidation of piperazine nitrogen as HIV-1 integrase inhibitor.

Beijing University of Technology

Design and synthesis of 4-(2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-7-yl)-N-(5-(piperazin-1-ylmethyl)pyridine-2-yl)pyrimidin-2-amine as a highly potent and selective cyclin-dependent kinases 4 and 6 inhibitors and the discovery of structure-activity relationships.

Beijing University of Technology