Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50047205
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 12nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 25nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154284(CHEMBL3775664 | US10106508, Compound II-2)
Affinity DataIC50: 53nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154289(CHEMBL3774947)
Affinity DataIC50: 63nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 68nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154288(CHEMBL3774906)
Affinity DataIC50: 90nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154259(CHEMBL3775112)
Affinity DataIC50: 99nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154260(CHEMBL3775536)
Affinity DataIC50: 116nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154256(CHEMBL3775046)
Affinity DataIC50: 138nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154255(CHEMBL3774926 | US10106508, Compound II-1)
Affinity DataIC50: 139nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154277(CHEMBL3774578 | US10106508, Compound II-3)
Affinity DataIC50: 163nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154287(CHEMBL3775459)
Affinity DataIC50: 187nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154257(CHEMBL3774396)
Affinity DataIC50: 211nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154290(CHEMBL3775285)
Affinity DataIC50: 245nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154284(CHEMBL3775664 | US10106508, Compound II-2)
Affinity DataIC50: 336nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154282(CHEMBL3775911)
Affinity DataIC50: 354nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154283(CHEMBL3774471)
Affinity DataIC50: 434nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154258(CHEMBL3775897)
Affinity DataIC50: 456nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154261(CHEMBL3774808)
Affinity DataIC50: 460nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154279(CHEMBL3775148)
Affinity DataIC50: 519nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154280(CHEMBL3774712)
Affinity DataIC50: 595nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154281(CHEMBL3774609)
Affinity DataIC50: 824nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154285(CHEMBL3774982)
Affinity DataIC50: 829nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154255(CHEMBL3774926 | US10106508, Compound II-1)
Affinity DataIC50: 880nMAssay Description:Inhibition of EGFR-T790M/L858 mutant (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154286(CHEMBL3774910 | US10106508, Compound II-4)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Beijing University of Technology

Curated by ChEMBL
LigandPNGBDBM50154278(CHEMBL3775372 | US10106508, Compound II-5)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wildtype EGFR (unknown origin) preincubated for 30 mins followed by addition of 2x ATP-substrate mixture measured after 1 hr by Kinase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed