Affinity DataKd: 243nMAssay Description:Binding affinity to LSD1/CoREST (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 463nMAssay Description:Binding affinity to LSD1/CoREST (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKd: 594nMAssay Description:Binding affinity to LSD1/CoREST (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKd: 243nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.56E+3nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.49E+3nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 147nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 83nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 84nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 75nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 81nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 356nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.85E+3nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 975nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 82nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 251nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 115nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 228nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 230nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 237nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 112nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 162nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 64nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 86nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 82nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 68nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 369nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 191nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 82nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 67nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 127nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 127nMAssay Description:Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.43E+5nMAssay Description:Inhibition of human LSD1-CoREST expressed in Escherichia coli assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 7.78E+3nMAssay Description:Inhibition of human LSD1-CoREST expressed in Escherichia coli assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 243nMAssay Description:Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3K4me peptide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology
Curated by ChEMBL
European Institute of Oncology
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology
Curated by ChEMBL
European Institute of Oncology
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using biotinylated H3K4me1 peptide as substrate preincubated for 2...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal His-SUMO tagged human LSD1 (172 to 852 residues)/His-tagged CoREST (286 to 482 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of recombinant human LSD1 (172 to 852 residues)/His-tagged human CoREST (286 to 482 residues) expressed in Escherichia coli BL21 (DE3) cel...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant LSD1/CoREST using ART(mK)QTARKSTGGKAPRKQLAGGK-biotin as substrate incubated for 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human recombinant LSD1/CoREST using ART(mK)QTARKSTGGKAPRKQLAGGK-biotin as substrate incubated for 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology
Curated by ChEMBL
European Institute of Oncology
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human LSD1 (172 to 852 residues)/His-tagged human CoREST (286 to 482 residues) expressed in Escherichia coli BL21 (DE3) cel...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant LSD1/CoREST using ART(mK)QTARKSTGGKAPRKQLAGGK-biotin as substrate incubated for 15 minsMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology
Curated by ChEMBL
European Institute of Oncology
Curated by ChEMBL
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A/REST corepressor 1(Human)
European Institute of Oncology
Curated by ChEMBL
European Institute of Oncology
Curated by ChEMBL
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant human KDM1A/CoREST complex expressed in Escherichia coli using [Lys(Me1)4]-Histone H3 (1 to 21 residues)-GGK(biotin) as sub...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant LSD1/CoREST using ART(mK)QTARKSTGGKAPRKQLAGGK-biotin as substrate incubated for 15 minsMore data for this Ligand-Target Pair
