Compile Data Set for Download or QSAR
Report error Found 16 of affinity data for UniProtKB/TrEMBL: Q9JHR7
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459189(CHEMBL4211248)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459187(CHEMBL4211765)
Affinity DataIC50: 44nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50525489(CHEMBL4556893)
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal His6-tagged mouse recombinant IDE Escherichia coli BL21 (DE3) cells using fluorogenic peptide Mca-RPPGFSAFK(Dnp)-OH as subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459188(CHEMBL4206878)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459190(CHEMBL4208119)
Affinity DataIC50: 74nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459181(CHEMBL4207403)
Affinity DataIC50: 77nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459180(CHEMBL4203249)
Affinity DataIC50: 86nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM209032(US9243038, 6b (trans olefin) | US9243038, 6a (cis ...)
Affinity DataIC50: 90nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM209045(US9243038, 20)
Affinity DataIC50: 90nMAssay Description:Macrocycles were assayed for IDE inhibition by monitoring cleavage of a substrate peptide containing a fluorophore-quencher pair such that cleavage o...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459191(CHEMBL4215687)
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459182(CHEMBL4210721)
Affinity DataIC50: 230nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459186(CHEMBL4216209)
Affinity DataIC50: 300nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459184(CHEMBL4203477)
Affinity DataIC50: 601nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459183(CHEMBL4208342)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50459185(CHEMBL4204003)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInsulin-degrading enzyme(Mouse)
Peking University Shenzhen Graduate School

Curated by ChEMBL
LigandPNGBDBM50458054(CHEBI:35862 | Albac 50 | Baci-Rx | Baciferm 50 | B...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of mouse His-tagged IDE (42 to 1019 residues) using fluorophore/quencher-tagged RPPGFSAFK(Dnp)-OH peptide as substrate preincubated for 10...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed