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Report error Found 18 of affinity data for UniProtKB/TrEMBL: Q9CYK2
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581435(CHEMBL5089539)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of mouse QPCT measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50237457(CHEMBL4097599)
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50612624(CHEMBL5287602)
Affinity DataIC50: 18nMAssay Description:Inhibition of mouse glutaminyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50299853(1-(3,4-Dimethoxyphenyl)-3-(3-(5-methyl-1H-imidazol...)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50519243(CHEMBL4589039)
Affinity DataIC50: 28nMAssay Description:Inhibition of mouse glutaminyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50612625(CHEMBL5269831)
Affinity DataIC50: 30nMAssay Description:Inhibition of mouse glutaminyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50612627(CHEMBL5282127)
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse glutaminyl cyclaseMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50581471(CHEMBL5081502)
Affinity DataIC50: 61nMAssay Description:Inhibition of mouse QPCT measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7887(1-benzylimidazole | 1-Benzylimidazole (BI) | CHEMB...)
Affinity DataKi:  6.40E+3nM ΔG°:  -30.1kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7970(diethyl(2-sulfanylethyl)amine | N-diethylcysteamin...)
Affinity DataKi:  1.09E+4nM ΔG°:  -28.8kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7884(1-methyl-1H-imidazole | US9138393, 1-Methylimidazo...)
Affinity DataKi:  2.30E+4nM ΔG°:  -26.9kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7969(dimethyl(2-sulfanylethyl)amine | N-dimethylcysteam...)
Affinity DataKi:  2.90E+4nM ΔG°:  -26.3kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7968(2-aminoethane-1-thiol | Cysteamine)
Affinity DataKi:  4.20E+4nM ΔG°:  -25.4kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7882(CHEMBL540 | 1H-imidazole | imidazole | Imidazole (...)
Affinity DataKi:  1.60E+5nM ΔG°:  -22.0kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7939(1H-1,3-benzodiazole | Benzimidazole | Benzimidazol...)
Affinity DataKi:  1.92E+5nM ΔG°:  -21.6kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7973(CHEMBL104943 | 2-aminoethan-1-ol | ethanolamine)
Affinity DataKi:  1.93E+7nM ΔG°:  -9.95kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7972(ethane-1,2-diamine | CHEMBL816 | ethylenediamine)
Affinity DataKi:  2.20E+7nM ΔG°:  -9.62kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Mouse)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM7971(2-sulfanylethan-1-ol | Mercaptoethanol)
Affinity DataKi:  2.58E+6nM ΔG°:  -15.0kJ/molepH: 8.0 T: 2°CAssay Description:QC activity was evaluated fluorometrically using Gln-AMC as substrate, and pyroglutamyl peptidase as the auxiliary enzyme. After conversion of Gln-AM...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed