Compile Data Set for Download or QSAR
Report error Found 444 of affinity data for UniProtKB/TrEMBL: Q95PM0
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50226103((2S,3R)-ethyl 3-((S)-2-((S)-2-(benzyloxycarbonyl)-...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM12042(L-trans-3-Carboxyoxiran-2-carbonyl-L-leucylagmatin...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesiense MVAT4 rhodesain expressed in Pichia pastoris using Z-FR-AMC as substrate by fluorometryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50229129(4-methyl-N-((S)-1-oxo-3-phenyl-1-((S)-5-phenyl-1-(...)
Affinity DataIC50: 5nMAssay Description:Inhibition of rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50229129(4-methyl-N-((S)-1-oxo-3-phenyl-1-((S)-5-phenyl-1-(...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311247((S)-4-methyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311248((S)-3-phenyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311250((S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50611827(CHEMBL5275445)
Affinity DataIC50: 16nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463157(CHEMBL4244656)
Affinity DataIC50: 20nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463153(CHEMBL4247075)
Affinity DataIC50: 26nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268555(6-(3-(furan-3-yl)benzylamino)-9-(3-hydroxypropyl)-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311246((S)-4-methyl-N-(5-phenyl-1-(phenylsulfonyl)pent-1-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50226104((2R,3S)-ethyl 3-((S)-2-((S)-2-(benzyloxycarbonyl)-...)
Affinity DataIC50: 30nMAssay Description:Inhibition of rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463142(CHEMBL4238441)
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463154(CHEMBL4251480)
Affinity DataIC50: 30nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463154(CHEMBL4251480)
Affinity DataIC50: 31nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157207((1E,2E)-1-(3,4-dichlorophenyl)-3-phenylprop-2-en-1...)
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157211((E)-(3,4-dichlorophenyl)(4-methylphenyl)methanone ...)
Affinity DataIC50: 38nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50114651((1E)-1-(3-bromophenyl)ethan-1-one thiosemicarbazon...)
Affinity DataIC50: 50nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311249((S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311251((S)-N-(5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157204((E)-2-(1-(3,4-dichlorophenyl)pentylidene)hydrazine...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157210((E)-(3,4-dichlorophenyl)(2-phenylcyclopropyl)metha...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157206((1Z)-1-(3,4-dichlorophenyl)-2-phenoxyethan-1-one t...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157205((1E)-1-(3,4-dichlorophenyl)-2-phenylethan-1-one th...)
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50148049((1E)-1-(1,1'-biphenyl-4-yl)ethan-1-one thiosemicar...)
Affinity DataIC50: 90nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50157209((1E)-1-(3,4-dichlorophenyl)-3-phenylpropan-1-one t...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50229129(4-methyl-N-((S)-1-oxo-3-phenyl-1-((S)-5-phenyl-1-(...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by fluorescence techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50311252((1R,2R)-2-(4-chlorobenzoyl)-N-((S)-5-phenyl-1-(phe...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain preincubated after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50114608((1E)-1-(3,4-dichlorophenyl)propan-1-one thiosemica...)
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463147(CHEMBL4237990)
Affinity DataIC50: 110nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463151(CHEMBL4249696)
Affinity DataIC50: 140nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50: 145nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50: 145nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463152(CHEMBL4242138)
Affinity DataIC50: 150nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463148(CHEMBL4247707)
Affinity DataIC50: 150nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50114613((1E)-1-(3-bromophenyl)propan-1-one thiosemicarbazo...)
Affinity DataIC50: 230nMAssay Description:Inhibitory concentration against rhodesain of Trypanosoma brucei rhodesienceMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268557(9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamin...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268616(9-(3-hydroxypropyl)-6-(3-(pyridin-3-yl)benzylamino...)
Affinity DataIC50: 260nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300773(6-(3-(1H-indol-6-yl)benzylamino)-9-(3-hydroxypropy...)
Affinity DataIC50: 260nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268554(6-(3-(furan-2-yl)benzylamino)-9-(3-hydroxypropyl)-...)
Affinity DataIC50: 310nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50148061((1Z)-1-{3-[(1E)-N-(aminocarbonothioyl)ethanehydraz...)
Affinity DataIC50: 330nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300774(N-(3'-((2-cyano-9-(3-hydroxypropyl)-9H-purin-6-yla...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268446(methyl 3'-((2-cyano-9-(3-hydroxypropyl)-9H-purin-6...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50300772(6-(3-(1H-indol-5-yl)benzylamino)-9-(3-hydroxypropy...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50148055((1E)-1-(3-phenoxyphenyl)ethan-1-one thiosemicarbaz...)
Affinity DataIC50: 550nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463145(CHEMBL4244085)
Affinity DataIC50: 560nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50463146(CHEMBL4240920)
Affinity DataIC50: 590nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandPNGBDBM50268668(6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 444 total ) | Next | Last >>
Jump to: