Compile Data Set for Download or QSAR
Report error Found 212 for UniProtKB: Q61239
LigandPNGBDBM13382(CHEMBL158553 | 3-(3-chlorophenyl)-4-{[(4-cyanophen...)
Affinity DataEC50:  5.20nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153164(N-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-N-(5...)
Affinity DataEC50:  16nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153167(6-{3-[3-(4-Cyano-benzyl)-3H-imidazol-4-yl]-3-hydro...)
Affinity DataEC50:  57.5nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126036(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataEC50:  0.100nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153170(6-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-me...)
Affinity DataEC50:  1.57nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153173(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataEC50:  21.9nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153175(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataEC50:  32nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153171(6-{3-[3-(4-Cyano-benzyl)-3H-imidazol-4-yl]-3-hydro...)
Affinity DataEC50:  16.7nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153168(6-({[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-am...)
Affinity DataEC50:  1.34nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153169(3-Benzo[1,3]dioxol-5-yl-4-[3-(4-cyano-benzyl)-3H-i...)
Affinity DataEC50:  1.65nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153176(4''-tert-Butyl-6-[3-(4-cyano-benzyl)-3H-imidazol-4...)
Affinity DataEC50: >100nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153174(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataEC50:  52nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153166(3''-Chloro-6-[3-(4-cyano-benzyl)-3H-imidazol-4-ylm...)
Affinity DataEC50:  7.70nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153177(N-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-N-(5...)
Affinity DataEC50:  100nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126041(6-[3-(4-Cyano-phenyl)-3-hydroxy-3-(3-methyl-3H-imi...)
Affinity DataEC50:  2.74nMAssay Description:Reduced farnesylation in H-Ras NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50151516(5-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataEC50:  15nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50151520(3-{4-(3-chlorophenyl)-5-[4-cyanophenyl(1-methyl-1H...)
Affinity DataEC50:  9nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50151519(4-[[1-(3-Chloro-benzyl)-4-(3-chloro-phenyl)-6-oxo-...)
Affinity DataEC50:  10nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50151515(4-[[4-(3-Chloro-phenyl)-1-(3-fluoro-benzyl)-6-oxo-...)
Affinity DataEC50:  15nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50135353(5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataEC50:  0.5nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50151521(4-(3-Chloro-phenyl)-5-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataEC50:  11nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126335(R-115777 | 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1...)
Affinity DataEC50:  1.60nMAssay Description:Inhibition of Ras farnesylation in H-Ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM14459((+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H...)
Affinity DataEC50:  100nMAssay Description:Inhibition of Ras farnesylation in H-Ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153781(4-[5-(4-cyano-benzyloxymethyl)-imidazol-1-ylmethyl...)
Affinity DataEC50:  461nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153166(3''-Chloro-6-[3-(4-cyano-benzyl)-3H-imidazol-4-ylm...)
Affinity DataEC50:  7.70nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153789(6-[5-(3''-Chloro-5-cyano-biphenyl-2-ylmethoxymethy...)
Affinity DataEC50:  155nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153783(5-[5-(2-Benzo[1,3]dioxol-5-yl-4-cyano-benzyloxymet...)
Affinity DataEC50:  16nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153174(6-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethoxymethy...)
Affinity DataEC50:  52nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153797(6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)me...)
Affinity DataEC50:  1.60nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153796(6-(((1-(4-chlorobenzyl)-1H-imidazol-5-yl)methoxy)m...)
Affinity DataEC50:  34nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153778(6-[3-(4-Cyano-3-naphthalen-1-yl-benzyl)-3H-imidazo...)
Affinity DataEC50:  60nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50126335(R-115777 | 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1...)
Affinity DataEC50:  1.60nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153791(6-((5-((2-(benzo[d][1,3]dioxol-5-yl)-4-cyanobenzyl...)
Affinity DataEC50:  29nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153792(4'-acetyl-6-(((1-(4-cyanobenzyl)-1H-imidazol-5-yl)...)
Affinity DataEC50:  77nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153785(4-((1-(4-cyanobenzyl)-1H-imidazol-5-yl)methoxy)-2-...)
Affinity DataEC50:  1.20nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50153776(5-((5-(((5-cyano-3'-ethoxybiphenyl-2-yl)methoxy)me...)
Affinity DataEC50:  17nMAssay Description:Inhibition of H-Ras transformed NIH-3T3-cell proliferationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157236(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157235(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  285nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157240(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  90nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157239(2''-Cyano-5''-[(4-cyano-benzyloxy)-(3-methyl-3H-im...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157242(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157247(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  120nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157237(2'',3''-Dichloro-5-[(4-cyano-benzyloxy)-(3-methyl-...)
Affinity DataEC50:  240nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157248(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataEC50:  420nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157252(5-[(3-Fluoro-4-trifluoromethyl-benzyloxy)-(3-methy...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157255(2'',4''-Dichloro-5-[(4-cyano-benzyloxy)-(3-methyl-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157254(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataEC50:  85nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157256(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50:  89nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50157246(6''-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(...)
Affinity DataEC50:  11nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17325(CHEMBL29982 | (2S)-2-[(4-{[butyl(2-cyclohexylethyl...)
Affinity DataEC50:  16nMAssay Description:Effective concentration against H-ras processing in NIH 3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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