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Report error Found 7 of affinity data for UniProtKB/TrEMBL: Q1HEC0
TargetAcetyl-CoA carboxylase(Rat)
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617({(3R)-1'-(anthracen-9-ylcarbonyl)[1,4'-bipiperidin...)
Affinity DataIC50: 55nMAssay Description:Inhibition of rat acetyl-CoA carboxylase 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetyl-CoA carboxylase(Rat)
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617({(3R)-1'-(anthracen-9-ylcarbonyl)[1,4'-bipiperidin...)
Affinity DataIC50: 61nMAssay Description:Inhibition of rat ACC2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetyl-CoA carboxylase(Rat)
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350750(CHEMBL1818300)
Affinity DataIC50: 150nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetyl-CoA carboxylase(Rat)
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50189617({(3R)-1'-(anthracen-9-ylcarbonyl)[1,4'-bipiperidin...)
Affinity DataIC50: 170nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetyl-CoA carboxylase(Rat)
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50350747(CHEMBL1818296)
Affinity DataIC50: 190nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetyl-CoA carboxylase(Rat)
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM97610(CHEMBL1630715 | US8470841, 35)
Affinity DataIC50: 400nMpH: 7.5 T: 2°CAssay Description:The reaction mixture contained 50 mM tris acetate (Merck, #1.08382.1000), pH 7.5, 250 μM acetyl coenzyme A (Sigma, #A2181),16 mM NaHCO3 (Merck, #1...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetAcetyl-CoA carboxylase(Rat)
Torrent Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM97624(US8470841, 59)
Affinity DataIC50: 1.50E+3nMpH: 7.5 T: 2°CAssay Description:The reaction mixture contained 50 mM tris acetate (Merck, #1.08382.1000), pH 7.5, 250 μM acetyl coenzyme A (Sigma, #A2181),16 mM NaHCO3 (Merck, #1...More data for this Ligand-Target Pair
In DepthDetails
US Patent