Compile Data Set for Download or QSAR
Report error Found 48 of affinity data for UniProtKB/TrEMBL: Q16828
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50607111(CHEMBL5218807)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MKP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM26613((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MKP3 using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50326052((E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of Myc-tagged human Dusp6 expressed in TPA-induced human HeLa cells assessed as decrease in dephosphorylation of pERK measured by immunost...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50544431(CHEMBL4637459 | US11192850, Entry 4k)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MKP3 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50544440(CHEMBL4647367 | US11192850, Entry 4t)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MKP3 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50378899(CHEMBL1672293)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant MKP3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50336847(2-(4-((5-(2-chlorophenyl)-6-(ethoxycarbonyl)-7-met...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of recombinant MKP3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM88776({4-[(5-(4-chlorophenyl)-6-(isopropoxycarbonyl)-7-m...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of recombinant MKP3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50336849(ethyl 7-methyl-3-oxo-5-(thiophen-2-yl)-2-(3,4,5-tr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant MKP3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50544427(CHEMBL4632818 | US11192850, Entry 4g)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MKP3 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis sp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50336848(2-(4-((6-(ethoxycarbonyl)-5-(3-methoxyphenyl)-7-me...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant MKP3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50378898(CHEMBL1672292)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant MKP3 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50343148(N1-(1-(4-(4-fluorophenyl)piperazin-1-yl)-1-(thioph...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MKP3 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MKP3 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50343142(N-(4-butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MKP3 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388815(CHEMBL2062528)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388813(CHEMBL2062708)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388816(CHEMBL2062710)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388817(CHEMBL2062711)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388818(CHEMBL2062712)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388819(CHEMBL2062713)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388820(CHEMBL2062714)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50250914(CHEMBL4091173)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3 (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2019
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558461(CHEMBL4760367)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558485(CHEMBL4800195)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50607110(CHEMBL5219519)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM82577(N-(4-fluoro-1,3-benzothiazol-2-yl)-5-(4-methoxyphe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant MKP3 (unknown origin) using OMFP as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388821(CHEMBL2062591)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388807(CHEMBL2062590)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388723(CHEMBL2057662)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3 using 3-O-Methylfluorescein phosphate as substrate incubated for 10 mins prior to substrate addition by fluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388814(CHEMBL2062709)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388822(CHEMBL2062592)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388823(CHEMBL2062593)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388824(CHEMBL2062594)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388825(CHEMBL2062595)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388808(CHEMBL2062596)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388809(CHEMBL2062597)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388810(CHEMBL2062598)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388811(CHEMBL2062599)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50388812(CHEMBL2062707)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558488(CHEMBL4794972)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MKP3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558487(CHEMBL4786243)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558486(CHEMBL4797766)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558484(CHEMBL4748824)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558483(CHEMBL4778085)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558482(CHEMBL4742123)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50558481(CHEMBL4783639)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed