Compile Data Set for Download or QSAR
Report error Found 415 for UniProtKB: Q14654
LigandPNGBDBM50190501(6-chloro-3-{[1-(trifluoromethyl)cyclopropyl]-amino...)
Affinity DataEC50:  530nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM86248(NSC_3019 | CAS_364-98-7 | diazoxide)
Affinity DataEC50:  3.30E+4nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50190500(6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...)
Affinity DataEC50:  180nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50190496(6-chloro-3-(1-phenylcyclopropyl)amino-4H-thieno[3,...)
Affinity DataEC50:  810nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50118359((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...)
Affinity DataEC50:  190nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50190502(6-bromo-3-(1-methylcyclopropyl)amino-4H-thieno[3,2...)
Affinity DataEC50:  160nMAssay Description:Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channelsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50118359((2-Chloro-7,7-dioxo-4,7-dihydro-1,7-dithia-4,6-dia...)
Affinity DataEC50:  190nMAssay Description:Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as repolarization of tolbutamide-induced membrane depolarizationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM86248(NSC_3019 | CAS_364-98-7 | diazoxide)
Affinity DataEC50:  3.10E+4nMAssay Description:Activity at Kir6.2/SUR1 KATP channels expressed in HEK293 cells assessed as activation of K+ currentsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119269(Cyclobutyl-(7-fluoro-1,1-dioxo-1,4-dihydro-1lambda...)
Affinity DataEC50:  356nMAssay Description:Inhibition of Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119273(N*3*-Cyclobutyl-1,1-dioxo-1,4-dihydro-1lambda*6*-b...)
Affinity DataEC50:  3.20E+4nMAssay Description:Negative log EC50 for Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119271(Cyclobutyl-(7-methoxy-1,1-dioxo-1,4-dihydro-1lambd...)
Affinity DataEC50:  4.00E+3nMAssay Description:Negative log EC50 for Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119270(Cyclobutyl-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo...)
Affinity DataEC50:  2.00E+3nMAssay Description:Negative log EC50 for Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119274(Cyclobutyl-(7-nitro-1,1-dioxo-1,4-dihydro-1lambda*...)
Affinity DataEC50:  530nMAssay Description:Inhibition of Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119273(N*3*-Cyclobutyl-1,1-dioxo-1,4-dihydro-1lambda*6*-b...)
Affinity DataEC50:  3.10E+4nMAssay Description:Inhibition of Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119271(Cyclobutyl-(7-methoxy-1,1-dioxo-1,4-dihydro-1lambd...)
Affinity DataEC50:  3.87E+3nMAssay Description:Inhibition of Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM86248(NSC_3019 | CAS_364-98-7 | diazoxide)
Affinity DataEC50:  8.80E+3nMAssay Description:Inhibition of Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119270(Cyclobutyl-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo...)
Affinity DataEC50:  1.96E+3nMAssay Description:Inhibition of Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119272((7-Chloro-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1...)
Affinity DataEC50:  196nMAssay Description:Inhibition of Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119272((7-Chloro-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1...)
Affinity DataEC50:  200nMAssay Description:Negative log EC50 for Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50119269(Cyclobutyl-(7-fluoro-1,1-dioxo-1,4-dihydro-1lambda...)
Affinity DataEC50:  400nMAssay Description:Negative log EC50 for Beta-cell KATP channelMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127776(1-(4-Chloro-phenyl)-3-[2-(2,2,2-trifluoro-1-hydrox...)
Affinity DataEC50:  276nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127775(N-[2-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-...)
Affinity DataEC50:  84nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127778(3,5-Dichloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-tri...)
Affinity DataEC50:  306nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127777(But-2-enoic acid [2-(2,2,2-trifluoro-1-hydroxy-1-t...)
Affinity DataEC50:  72nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127779(2-Methyl-pentanoic acid [2-(2,2,2-trifluoro-1-hydr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127780(Benzo[b]thiophene-2-carboxylic acid [2-(2,2,2-trif...)
Affinity DataEC50: >1.00E+4nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127781(N-[5-Hydroxy-2-(2,2,2-trifluoro-1-hydroxy-1-triflu...)
Affinity DataEC50:  137nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127783(N-[2-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-...)
Affinity DataEC50:  60nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127782(2-Ethyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...)
Affinity DataEC50:  4.34E+3nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127785(4-Bromo-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...)
Affinity DataEC50:  47nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127786(N-[2-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-...)
Affinity DataEC50:  131nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127795(4-Methoxy-N-[2-(2,2,2-trifluoro-1-hydroxy-1-triflu...)
Affinity DataEC50:  417nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127787(2-Methoxy-N-[2-(2,2,2-trifluoro-1-hydroxy-1-triflu...)
Affinity DataEC50:  213nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127796(2-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataEC50:  1.77E+5nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127790(3-Phenyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataEC50:  1.75E+3nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127791(4-Chloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataEC50:  570nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127788(3-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataEC50:  23nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127784(N-[2-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-...)
Affinity DataEC50:  160nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127789(Cyclopentanecarboxylic acid [2-(2,2,2-trifluoro-1-...)
Affinity DataEC50:  495nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127792(3-Fluoro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataEC50:  44nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127794(Furan-2-carboxylic acid [2-(2,2,2-trifluoro-1-hydr...)
Affinity DataEC50:  9nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127793(Oxazole-5-carboxylic acid [2-(2,2,2-trifluoro-1-hy...)
Affinity DataEC50:  24nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127801(N-[2-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-...)
Affinity DataEC50:  15nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127797(3-Bromo-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...)
Affinity DataEC50:  80nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127798(Thiophene-2-carboxylic acid [2-(2,2,2-trifluoro-1-...)
Affinity DataEC50:  12nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127799(N-[2-(2,2,2-Trifluoro-1-hydroxy-1-trifluoromethyl-...)
Affinity DataEC50:  44nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127802(3-Chloro-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataEC50:  98nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127803(N-[4-Bromo-2-(2,2,2-trifluoro-1-hydroxy-1-trifluor...)
Affinity DataEC50:  5.31E+3nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127800(Cyclopropanecarboxylic acid [2-(2,2,2-trifluoro-1-...)
Affinity DataEC50:  751nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-sensitive inward rectifier potassium channel 11(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127805(2-Methyl-N-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluo...)
Affinity DataEC50:  5.55E+3nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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