Compile Data Set for Download or QSAR
Report error Found 20 for UniProtKB: Q13586
LigandPNGBDBM50575331(CHEMBL4868242)
Affinity DataIC50: 76nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50575336(CHEMBL4753998)
Affinity DataIC50: 119nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin)More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50549365(CHEMBL3403742)
Affinity DataIC50: 228nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50549358(CHEMBL4753023)
Affinity DataIC50: 361nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50450626(CHEMBL4162723)
Affinity DataIC50: 600nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM50549357(CHEMBL4794288)
Affinity DataIC50: 781nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549360(CHEMBL4780000)
Affinity DataIC50: 802nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549363(CHEMBL4751678)
Affinity DataIC50: 807nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549362(CHEMBL4761656)
Affinity DataIC50: 851nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549356(CHEMBL4799904)
Affinity DataIC50: 866nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50575336(CHEMBL4753998)
Affinity DataIC50: 895nMAssay Description:Inhibition of Orai2/STIM1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50575334(CHEMBL4863881)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549359(CHEMBL4750981)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549361(CHEMBL4742227)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50549364(CHEMBL4742960)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromal interaction molecule 1(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50450629(CHEMBL4177187)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of STIM1/STIM2/Orai1 (unknown origin) expressed in mouse BV2 cells assessed as reduction of store-operated calcium entry at 100 uM preincu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50575335(CHEMBL4570175)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human STIM1/Orai1 expressed in HEK293 cells assessed as reduction in Orai1 current by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50575335(CHEMBL4570175)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human STIM1/Orai3 expressed in HEK293 cells assessed as reduction in Orai3 current by electrophysiological methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50018011(CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromal interaction molecule 1(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50450626(CHEMBL4162723)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of STIM1/STIM2/Orai1 (unknown origin) expressed in mouse BV2 cells assessed as induction of store-operated calcium entry by measuring resi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed