Compile Data Set for Download or QSAR
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TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672866(US20240150287, Example 35 | (S)-3-(4-(7-methoxy-3-...)
Affinity DataIC50: 0.450nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672848(US20240150287, Example 16 | (S)-3-(4-(2′-oxo...)
Affinity DataIC50: 0.75nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672853(US20240150287, Example 22 | (S)-3-(4-(7-chloro-3-m...)
Affinity DataIC50: 1.19nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672867(US20240150287, Example 36 | (S)-3-(4-(6-(dimethyla...)
Affinity DataIC50: 1.51nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672861(US20240150287, Example 30 | (S)-3-(4-(7-fluoro-3-m...)
Affinity DataIC50: 1.83nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672836(US20240150287, Example 4 | (S)-3-(4-(6′-fluo...)
Affinity DataIC50: 2.54nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672834(US20240150287, Example 2 | (S)-3-(4-(7′-chlo...)
Affinity DataIC50: 2.57nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672864(US20240150287, Example 33 | (S)-3-(4-(6,7-difluoro...)
Affinity DataIC50: 2.70nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672837(US20240150287, Example 5 | (Step 1) (S)-3-(4-(7...)
Affinity DataIC50: 2.87nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672843(US20240150287, Example 11 | (S)-3-(4-(6′-(di...)
Affinity DataIC50: 3.05nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672870(US20240150287, Example 39 | (S)-3-(4-(7-chloro-3-m...)
Affinity DataIC50: 3.65nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672851(US20240150287, Example 20 | (2S)-2-(4-(2-oxa-5-aza...)
Affinity DataIC50: 4.15nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672844(US20240150287, Example 12 | (S)-3-(4-(5′-(di...)
Affinity DataIC50: 4.15nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672863(US20240150287, Example 32 | (S)-3-(4-(5,6-dichloro...)
Affinity DataIC50: 4.19nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672868(US20240150287, Example 37 | (S)-3-(4-(5-(dimethyla...)
Affinity DataIC50: 5.09nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672862(US20240150287, Example 31 | (S)-3-(4-(5,7-difluoro...)
Affinity DataIC50: 5.34nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672835(US20240150287, Example 3 | (S)-3-(4-(7′-meth...)
Affinity DataIC50: 5.48nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672847(US20240150287, Example 15 | (S)-3-(4-(6′,7&#...)
Affinity DataIC50: 5.62nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672855(US20240150287, Example 24 | (S)-3-(4-(6-chloro-3-c...)
Affinity DataIC50: 5.67nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672838(US20240150287, Example 6 | (S)-3-(4-(2′-oxos...)
Affinity DataIC50: 5.81nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672837(US20240150287, Example 5 | (Step 1) (S)-3-(4-(7...)
Affinity DataIC50: 6.21nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672856(US20240150287, Example 25 | (S)-3-(4-(7-chloro-3-c...)
Affinity DataIC50: 7.5nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672836(US20240150287, Example 4 | (S)-3-(4-(6′-fluo...)
Affinity DataIC50: 8.02nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672858(US20240150287, Example 27 | (S)-3-(4-(3-cyclopropy...)
Affinity DataIC50: 8.81nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672865(US20240150287, Example 34 | (S)-3-(4-(4,5-difluoro...)
Affinity DataIC50: 10.5nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672859(US20240150287, Example 28 | (S)-3-(4-(7-chloro-2-o...)
Affinity DataIC50: 10.9nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672850(US20240150287, Example 19 | (S)-3-(4-(7′-chl...)
Affinity DataIC50: 11.4nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672833(US20240150287, Example 1 | (S)-3-(4-(5′,6...)
Affinity DataIC50: 14.3nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672839(US20240150287, Example 7 | (S)-3-(4-(7-chloro-2-ox...)
Affinity DataIC50: 16.1nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672840(US20240150287, Example 8 | (S)-3-(4-(6′-chlo...)
Affinity DataIC50: 17.6nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672860(US20240150287, Example 29 | (S)-3-(4-(7-chloro-3-(...)
Affinity DataIC50: 18.1nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672852(US20240150287, Example 21 | (S)-3-(4-(7′-chl...)
Affinity DataIC50: 23.8nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672869(US20240150287, Example 38 | (S)-3-(4-(7-chloro-3-m...)
Affinity DataIC50: 27.9nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672842(US20240150287, Example 10 | (S)-3-(4-(7-chloro-3,3...)
Affinity DataIC50: 38.8nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672849(US20240150287, Example 17 | (S)-3-(4-(7′-chl...)
Affinity DataIC50: 64.2nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672841(US20240150287, Example 9 | (S)-3-(4-(5′-fluo...)
Affinity DataIC50: 95.5nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672854(US20240150287, Example 23 | (S)-3-(4-(5-chloro-3-c...)
Affinity DataIC50: 143nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMucosal addressin cell adhesion molecule 1/Integrin alpha-4/beta-7(Human)
Hangzhou Apeloa Medicine Research Institute Co.

US Patent
LigandPNGBDBM672857(US20240150287, Example 26 | (S)-3-(4-(7-chloro-3-m...)
Affinity DataIC50: 160nMAssay Description:Coat the 96-well microplate (Costar) with 50 μL of recombinant human MAdCAM-1 (R&D Systems) solution per well, and incubate overnight (12-18 hou...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50291325((S)-3-((S)-2-Acetylamino-4-methyl-pentanoylamino)-...)
Affinity DataIC50: 1.26E+5nMAssay Description:The concentration of compound required to prevent 50 percent of cells from adhering to MAdCAM-1More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50291324(4-((S)-2-Acetylamino-4-methyl-pentanoylamino)-3-((...)
Affinity DataIC50: 2.19E+5nMAssay Description:The concentration of compound required to prevent 50 percent of cells from adhering to MAdCAM-1More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50070605((S)-3-((S)-2-Acetylamino-4-methyl-pentanoylamino)-...)
Affinity DataIC50: 2.76E+5nMAssay Description:The concentration of compound required to prevent 50 percent of cells from adhering to MAdCAM-1More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50291323(3-{1-[1-(1-carbamoyl-3-methylbutylcarbamoyl)-2-hyd...)
Affinity DataIC50: 2.98E+5nMAssay Description:The concentration of compound required to prevent 50 percent of cells from adhering to MAdCAM-1More data for this Ligand-Target Pair
In DepthDetails Article

LigandPNGBDBM50291322(4-((S)-2-Acetylamino-4-methyl-pentanoylamino)-3-((...)
Affinity DataIC50: 5.00E+5nMAssay Description:The concentration of compound required to prevent 50 percent of cells from adhering to MAdCAM-1More data for this Ligand-Target Pair
In DepthDetails Article