Affinity DataEC50: 1.02E+4nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+4nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
Affinity DataEC50: 272nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
Affinity DataEC50: 83nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
Affinity DataEC50: 1.05E+5nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+4nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2B receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 5.10nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain striatumMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 15.2nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain thalamusMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 5.40nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain thalamusMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 5.90nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain olfactory tubercleMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 1.90nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain olfactory tubercleMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 9.30nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain striatumMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 9.80nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain cortexMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 3.20nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain cortexMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 9.10nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain hippocampusMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Institute of Biomedical Imaging (I2Bm)
Curated by ChEMBL
Affinity DataKd: 7.10nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain hippocampusMore data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.90E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 7.10E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 720nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.90E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.30E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.40E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 9.30E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 6.10E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.80E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 670nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+5nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glycine-induce...More data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 9.30E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 7.20E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 5.30E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.40E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 840nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 550nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+3nMAssay Description:Positive allosteric modulation of recombinant rat GluN1/GluN2B receptor expressed in xenopus laevis oocyte assessed as potentiation of glutamate and ...More data for this Ligand-Target Pair
